Edelstein LC - Search Results

1

Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race.

Edelstein LC, Simon LM, Lindsay CR, Kong X, Teruel-Montoya R, Tourdot BE, Chen ES, Ma L, Coughlin S, Nieman M, Holinstat M, Shaw CA, Bray PF. Edelstein LC, et al. Blood. 2014 Nov 27;124(23):3450-8. doi: 10.1182/blood-2014-04-572479. Epub 2014 Oct 7. Blood. 2014. PMID: 25293779 Free PMC article.

2

The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y₁₂ inhibition.

Whitley MJ, Henke DM, Ghazi A, Nieman M, Stoller M, Simon LM, Chen E, Vesci J, Holinstat M, McKenzie SE, Shaw CA, Edelstein LC, Bray PF. Whitley MJ, et al. Among authors: edelstein lc. J Thromb Haemost. 2018 Dec;16(12):2501-2514. doi: 10.1111/jth.14318. Epub 2018 Nov 22. J Thromb Haemost. 2018. PMID: 30347494 Free PMC article.

3

MicroRNAs in platelet production and activation.

Edelstein LC, Bray PF. Edelstein LC, et al. Blood. 2011 May 19;117(20):5289-96. doi: 10.1182/blood-2011-01-292011. Epub 2011 Mar 1. Blood. 2011. PMID: 21364189 Free PMC article. Review.

4

Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

Nagalla S, Shaw C, Kong X, Kondkar AA, Edelstein LC, Ma L, Chen J, McKnight GS, López JA, Yang L, Jin Y, Bray MS, Leal SM, Dong JF, Bray PF. Nagalla S, et al. Among authors: edelstein lc. Blood. 2011 May 12;117(19):5189-97. doi: 10.1182/blood-2010-09-299719. Epub 2011 Mar 17. Blood. 2011. PMID: 21415270 Free PMC article.

5

Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c.

Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF. Edelstein LC, et al. Nat Med. 2013 Dec;19(12):1609-16. doi: 10.1038/nm.3385. Epub 2013 Nov 10. Nat Med. 2013. PMID: 24216752 Free PMC article.

6

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.

Simon LM, Edelstein LC, Nagalla S, Woodley AB, Chen ES, Kong X, Ma L, Fortina P, Kunapuli S, Holinstat M, McKenzie SE, Dong JF, Shaw CA, Bray PF. Simon LM, et al. Among authors: edelstein lc. Blood. 2014 Apr 17;123(16):e37-45. doi: 10.1182/blood-2013-12-544692. Epub 2014 Feb 12. Blood. 2014. PMID: 24523238 Free PMC article.

7

Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis.

Tourdot BE, Conaway S, Niisuke K, Edelstein LC, Bray PF, Holinstat M. Tourdot BE, et al. Among authors: edelstein lc. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2644-50. doi: 10.1161/ATVBAHA.114.304249. Epub 2014 Oct 2. Arterioscler Thromb Vasc Biol. 2014. PMID: 25278289 Free PMC article.

8

Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.

Zhou Y, Abraham S, Andre P, Edelstein LC, Shaw CA, Dangelmaier CA, Tsygankov AY, Kunapuli SP, Bray PF, McKenzie SE. Zhou Y, et al. Among authors: edelstein lc. Blood. 2015 Dec 24;126(26):2871-81. doi: 10.1182/blood-2015-02-631135. Epub 2015 Oct 29. Blood. 2015. PMID: 26516227 Free PMC article.

9

MicroRNAs in Platelet Physiology and Function.

Lindsay CR, Edelstein LC. Lindsay CR, et al. Among authors: edelstein lc. Semin Thromb Hemost. 2016 Apr;42(3):215-22. doi: 10.1055/s-0035-1570077. Epub 2016 Mar 7. Semin Thromb Hemost. 2016. PMID: 26951501 Review.

10

Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.

Simon LM, Chen ES, Edelstein LC, Kong X, Bhatlekar S, Rigoutsos I, Bray PF, Shaw CA. Simon LM, et al. Among authors: edelstein lc. Am J Hum Genet. 2016 May 5;98(5):883-897. doi: 10.1016/j.ajhg.2016.03.007. Epub 2016 Apr 28. Am J Hum Genet. 2016. PMID: 27132591 Free PMC article.

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