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Page 1
Genetic architecture of oral glucose-stimulated insulin release provides biological insights into type 2 diabetes aetiology.
Madsen AL, Bonàs-Guarch S, Gheibi S, Prasad R, Vangipurapu J, Ahuja V, Cataldo LR, Dwivedi O, Hatem G, Atla G, Guindo-Martínez M, Jørgensen AM, Jonsson AE, Miguel-Escalada I, Hassan S, Linneberg A, Ahluwalia TS, Drivsholm T, Pedersen O, Sørensen TIA, Astrup A, Witte D, Damm P, Clausen TD, Mathiesen E, Pers TH, Loos RJF, Hakaste L, Fex M, Grarup N, Tuomi T, Laakso M, Mulder H, Ferrer J, Hansen T. Madsen AL, et al. Among authors: pers th. Nat Metab. 2024 Oct;6(10):1897-1912. doi: 10.1038/s42255-024-01140-6. Epub 2024 Oct 17. Nat Metab. 2024. PMID: 39420167 Free PMC article.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla L, Dolgalev G, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Völzke H, Dörr M, Falkai P, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Trastulla L, et al. Nat Commun. 2024 Jul 1;15(1):5534. doi: 10.1038/s41467-024-49338-2. Nat Commun. 2024. PMID: 38951512 Free PMC article.
GLP-1-directed NMDA receptor antagonism for obesity treatment.
Petersen J, Ludwig MQ, Juozaityte V, Ranea-Robles P, Svendsen C, Hwang E, Kristensen AW, Fadahunsi N, Lund J, Breum AW, Mathiesen CV, Sachs L, Moreno-Justicia R, Rohlfs R, Ford JC, Douros JD, Finan B, Portillo B, Grose K, Petersen JE, Trauelsen M, Feuchtinger A, DiMarchi RD, Schwartz TW, Deshmukh AS, Thomsen MB, Kohlmeier KA, Williams KW, Pers TH, Frølund B, Strømgaard K, Klein AB, Clemmensen C. Petersen J, et al. Among authors: pers th. Nature. 2024 May;629(8014):1133-1141. doi: 10.1038/s41586-024-07419-8. Epub 2024 May 15. Nature. 2024. PMID: 38750368 Free PMC article.
Assessing household lifestyle exposures from consumer purchases, the My Purchases cohort.
Møller FT, Junker TG, Kold Sørensen K, Eves C, Wohlfahrt J, Dillner J, Torp-Pedersen C, Wilkowski B, Chong S, Pers TH, Yakimov V, Müller H, Ethelberg S, Melbye M. Møller FT, et al. Among authors: pers th. Sci Rep. 2023 Dec 7;13(1):21601. doi: 10.1038/s41598-023-47534-6. Sci Rep. 2023. PMID: 38062070 Free PMC article.
Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety.
Webster AN, Becker JJ, Li C, Schwalbe DC, Kerspern D, Karolczak EO, Bundon C, Onoharigho RA, Crook M, Jalil M, Godschall EN, Dame EG, Dawer A, Belmont-Rausch DM, Pers TH, Lutas A, Habib N, Guler AD, Krashes MJ, Campbell JN. Webster AN, et al. Among authors: pers th. bioRxiv [Preprint]. 2024 Jul 12:2023.10.31.564990. doi: 10.1101/2023.10.31.564990. bioRxiv. 2024. PMID: 37961449 Free PMC article. Preprint.
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Lagou V, Jiang L, Ulrich A, Zudina L, González KSG, Balkhiyarova Z, Faggian A, Maina JG, Chen S, Todorov PV, Sharapov S, David A, Marullo L, Mägi R, Rujan RM, Ahlqvist E, Thorleifsson G, Gao Η, Εvangelou Ε, Benyamin B, Scott RA, Isaacs A, Zhao JH, Willems SM, Johnson T, Gieger C, Grallert H, Meisinger C, Müller-Nurasyid M, Strawbridge RJ, Goel A, Rybin D, Albrecht E, Jackson AU, Stringham HM, Corrêa IR Jr, Farber-Eger E, Steinthorsdottir V, Uitterlinden AG, Munroe PB, Brown MJ, Schmidberger J, Holmen O, Thorand B, Hveem K, Wilsgaard T, Mohlke KL, Wang Z; GWA-PA Consortium; Shmeliov A, den Hoed M, Loos RJF, Kratzer W, Haenle M, Koenig W, Boehm BO, Tan TM, Tomas A, Salem V, Barroso I, Tuomilehto J, Boehnke M, Florez JC, Hamsten A, Watkins H, Njølstad I, Wichmann HE, Caulfield MJ, Khaw KT, van Duijn CM, Hofman A, Wareham NJ, Langenberg C, Whitfield JB, Martin NG, Montgomery G, Scapoli C, Tzoulaki I, Elliott P, Thorsteinsdottir U, Stefansson K, Brittain EL, McCarthy MI, Froguel P, Sexton PM, Wootten D, Groop L, Dupuis J, Meigs JB, Deganutti G, Demirkan A, Pers TH, Reynolds CA, Aulchenko YS, Kaakinen MA, Jones B, Prokopenko I; Meta-Analysis of Glucose and Insulin-Related Traits … See abstract for full author list ➔ Lagou V, et al. Among authors: pers th. Nat Genet. 2023 Sep;55(9):1448-1461. doi: 10.1038/s41588-023-01462-3. Epub 2023 Sep 7. Nat Genet. 2023. PMID: 37679419 Free PMC article.
150 results