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Page 1
Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men.
Freitag-Wolf S, Dommisch H, Graetz C, Jockel-Schneider Y, Harks I, Staufenbiel I, Meyle J, Eickholz P, Noack B, Bruckmann C, Gieger C, Jepsen S, Lieb W, Schreiber S, König IR, Schaefer AS. Freitag-Wolf S, et al. Among authors: bruckmann c. J Clin Periodontol. 2014 Dec;41(12):1115-21. doi: 10.1111/jcpe.12317. Epub 2014 Nov 11. J Clin Periodontol. 2014. PMID: 25256105
Validation of reported genetic risk factors for periodontitis in a large-scale replication study.
Schaefer AS, Bochenek G, Manke T, Nothnagel M, Graetz C, Thien A, Jockel-Schneider Y, Harks I, Staufenbiel I, Wijmenga C, Eberhard J, Guzeldemir-Akcakanat E, Cine N, Folwaczny M, Noack B, Meyle J, Eickholz P, Trombelli L, Scapoli C, Nohutcu R, Bruckmann C, Doerfer C, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. Among authors: bruckmann c. J Clin Periodontol. 2013 Jun;40(6):563-72. doi: 10.1111/jcpe.12092. Epub 2013 Apr 16. J Clin Periodontol. 2013. PMID: 23587006
SLC23A1 polymorphism rs6596473 in the vitamin C transporter SVCT1 is associated with aggressive periodontitis.
de Jong TM, Jochens A, Jockel-Schneider Y, Harks I, Dommisch H, Graetz C, Flachsbart F, Staufenbiel I, Eberhard J, Folwaczny M, Noack B, Meyle J, Eickholz P, Gieger C, Grallert H, Lieb W, Franke A, Nebel A, Schreiber S, Doerfer C, Jepsen S, Bruckmann C, van der Velden U, Loos BG, Schaefer AS. de Jong TM, et al. Among authors: bruckmann c. J Clin Periodontol. 2014 Jun;41(6):531-40. doi: 10.1111/jcpe.12253. J Clin Periodontol. 2014. PMID: 24708273
A large candidate-gene association study suggests genetic variants at IRF5 and PRDM1 to be associated with aggressive periodontitis.
Schaefer AS, Jochens A, Dommisch H, Graetz C, Jockel-Schneider Y, Harks I, Staufenbiel I, Meyle J, Eickholz P, Folwaczny M, Laine M, Noack B, Wijmenga C, Lieb W, Bruckmann C, Schreiber S, Jepsen S, Loos BG. Schaefer AS, et al. Among authors: bruckmann c. J Clin Periodontol. 2014 Dec;41(12):1122-31. doi: 10.1111/jcpe.12314. Epub 2014 Nov 15. J Clin Periodontol. 2014. PMID: 25263394
Genetic evidence for PLASMINOGEN as a shared genetic risk factor of coronary artery disease and periodontitis.
Schaefer AS, Bochenek G, Jochens A, Ellinghaus D, Dommisch H, Güzeldemir-Akçakanat E, Graetz C, Harks I, Jockel-Schneider Y, Weinspach K, Meyle J, Eickholz P, Linden GJ, Cine N, Nohutcu R, Weiss E, Houri-Haddad Y, Iraqi F, Folwaczny M, Noack B, Strauch K, Gieger C, Waldenberger M, Peters A, Wijmenga C, Yilmaz E, Lieb W, Rosenstiel P, Doerfer C, Bruckmann C, Erdmann J, König I, Jepsen S, Loos BG, Schreiber S. Schaefer AS, et al. Among authors: bruckmann c. Circ Cardiovasc Genet. 2015 Feb;8(1):159-67. doi: 10.1161/CIRCGENETICS.114.000554. Epub 2014 Dec 2. Circ Cardiovasc Genet. 2015. PMID: 25466412 Clinical Trial.
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, Wellmann J, Berger K, Krone B, Hoffmann P, van der Velde N, Uitterlinden AG, de Groot LCPGM, Sawalha AH, Direskeneli H, Saruhan-Direskeneli G, Guzeldemir-Akcakanat E, Keceli HG, Laudes M, Noack B, Teumer A, Holtfreter B, Kocher T, Eickholz P, Meyle J, Doerfer C, Bruckmann C, Lieb W, Franke A, Schreiber S, Nohutcu RM, Erdmann J, Loos BG, Jepsen S, Dommisch H, Schaefer AS. Munz M, et al. Among authors: bruckmann c. Hum Mol Genet. 2017 Jul 1;26(13):2577-2588. doi: 10.1093/hmg/ddx151. Hum Mol Genet. 2017. PMID: 28449029
A haplotype block downstream of plasminogen is associated with chronic and aggressive periodontitis.
Munz M, Chen H, Jockel-Schneider Y, Adam K, Hoffman P, Berger K, Kocher T, Meyle J, Eickholz P, Doerfer C, Laudes M, Uitterlinden A, Lieb W, Franke A, Schreiber S, Offenbacher S, Divaris K, Bruckmann C, Loos BG, Jepsen S, Dommisch H, Schäefer AS. Munz M, et al. Among authors: bruckmann c. J Clin Periodontol. 2017 Oct;44(10):962-970. doi: 10.1111/jcpe.12749. Epub 2017 Sep 11. J Clin Periodontol. 2017. PMID: 28548211
A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.
Munz M, Willenborg C, Richter GM, Jockel-Schneider Y, Graetz C, Staufenbiel I, Wellmann J, Berger K, Krone B, Hoffmann P, van der Velde N, Uitterlinden AG, de Groot LCPGM, Sawalha AH, Direskeneli H, Saruhan-Direskeneli G, Guzeldemir-Akcakanat E, Keceli HG, Laudes M, Noack B, Teumer A, Holtfreter B, Kocher T, Eickholz P, Meyle J, Doerfer C, Bruckmann C, Lieb W, Franke A, Schreiber S, Nohutcu RM, Erdmann J, Loos BG, Jepsen S, Dommisch H, Schaefer AS. Munz M, et al. Among authors: bruckmann c. Hum Mol Genet. 2018 Mar 1;27(5):941-942. doi: 10.1093/hmg/ddy015. Hum Mol Genet. 2018. PMID: 29346566 No abstract available.
Genome-wide association meta-analysis of coronary artery disease and periodontitis reveals a novel shared risk locus.
Munz M, Richter GM, Loos BG, Jepsen S, Divaris K, Offenbacher S, Teumer A, Holtfreter B, Kocher T, Bruckmann C, Jockel-Schneider Y, Graetz C, Munoz L, Bhandari A, Tennstedt S, Staufenbiel I, van der Velde N, Uitterlinden AG, de Groot LCPGM, Wellmann J, Berger K, Krone B, Hoffmann P, Laudes M, Lieb W, Franke A, Dommisch H, Erdmann J, Schaefer AS. Munz M, et al. Among authors: bruckmann c. Sci Rep. 2018 Sep 12;8(1):13678. doi: 10.1038/s41598-018-31980-8. Sci Rep. 2018. PMID: 30209331 Free PMC article.
Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci.
Munz M, Richter GM, Loos BG, Jepsen S, Divaris K, Offenbacher S, Teumer A, Holtfreter B, Kocher T, Bruckmann C, Jockel-Schneider Y, Graetz C, Ahmad I, Staufenbiel I, van der Velde N, Uitterlinden AG, de Groot LCPGM, Wellmann J, Berger K, Krone B, Hoffmann P, Laudes M, Lieb W, Franke A, Erdmann J, Dommisch H, Schaefer AS. Munz M, et al. Among authors: bruckmann c. Eur J Hum Genet. 2019 Jan;27(1):102-113. doi: 10.1038/s41431-018-0265-5. Epub 2018 Sep 14. Eur J Hum Genet. 2019. PMID: 30218097 Free PMC article.
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