Rubin JB - Search Results

1

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma.

Barone A, Sengupta R, Warrington NM, Smith E, Wen PY, Brekken RA, Romagnoli B, Douglas G, Chevalier E, Bauer MP, Dembowsky K, Piwnica-Worms D, Rubin JB. Barone A, et al. Among authors: rubin jb. Oncotarget. 2014 Oct 30;5(20):9811-22. doi: 10.18632/oncotarget.2443. Oncotarget. 2014. PMID: 25238146 Free PMC article.

2

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

Rubin JB, Kung AL, Klein RS, Chan JA, Sun Y, Schmidt K, Kieran MW, Luster AD, Segal RA. Rubin JB, et al. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13513-8. doi: 10.1073/pnas.2235846100. Epub 2003 Oct 31. Proc Natl Acad Sci U S A. 2003. PMID: 14595012 Free PMC article.

3

Widespread CXCR4 activation in astrocytomas revealed by phospho-CXCR4-specific antibodies.

Woerner BM, Warrington NM, Kung AL, Perry A, Rubin JB. Woerner BM, et al. Among authors: rubin jb. Cancer Res. 2005 Dec 15;65(24):11392-9. doi: 10.1158/0008-5472.CAN-05-0847. Cancer Res. 2005. PMID: 16357147

4

Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo.

Yang L, Jackson E, Woerner BM, Perry A, Piwnica-Worms D, Rubin JB. Yang L, et al. Among authors: rubin jb. Cancer Res. 2007 Jan 15;67(2):651-8. doi: 10.1158/0008-5472.CAN-06-2762. Cancer Res. 2007. PMID: 17234775

5

Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.

Warrington NM, Woerner BM, Daginakatte GC, Dasgupta B, Perry A, Gutmann DH, Rubin JB. Warrington NM, et al. Among authors: rubin jb. Cancer Res. 2007 Sep 15;67(18):8588-95. doi: 10.1158/0008-5472.CAN-06-2220. Cancer Res. 2007. PMID: 17875698

6

Targeted inhibition of cyclic AMP phosphodiesterase-4 promotes brain tumor regression.

Goldhoff P, Warrington NM, Limbrick DD Jr, Hope A, Woerner BM, Jackson E, Perry A, Piwnica-Worms D, Rubin JB. Goldhoff P, et al. Among authors: rubin jb. Clin Cancer Res. 2008 Dec 1;14(23):7717-25. doi: 10.1158/1078-0432.CCR-08-0827. Clin Cancer Res. 2008. PMID: 19047098 Free PMC article.

7

Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons.

Sengupta R, Burbassi S, Shimizu S, Cappello S, Vallee RB, Rubin JB, Meucci O. Sengupta R, et al. Among authors: rubin jb. J Neurosci. 2009 Feb 25;29(8):2534-44. doi: 10.1523/JNEUROSCI.5865-08.2009. J Neurosci. 2009. PMID: 19244528 Free PMC article.

8

Cyclic AMP suppression is sufficient to induce gliomagenesis in a mouse model of neurofibromatosis-1.

Warrington NM, Gianino SM, Jackson E, Goldhoff P, Garbow JR, Piwnica-Worms D, Gutmann DH, Rubin JB. Warrington NM, et al. Among authors: rubin jb. Cancer Res. 2010 Jul 15;70(14):5717-27. doi: 10.1158/0008-5472.CAN-09-3769. Epub 2010 Jun 15. Cancer Res. 2010. PMID: 20551058 Free PMC article.

9

CXCL12 alone is insufficient for gliomagenesis in Nf1 mutant mice.

Sun T, Gianino SM, Jackson E, Piwnica-Worms D, Gutmann DH, Rubin JB. Sun T, et al. Among authors: rubin jb. J Neuroimmunol. 2010 Jul 27;224(1-2):108-13. doi: 10.1016/j.jneuroim.2010.05.002. J Neuroimmunol. 2010. PMID: 20554030 Free PMC article.

10

Treating brain tumors with PDE4 inhibitors.

Sengupta R, Sun T, Warrington NM, Rubin JB. Sengupta R, et al. Among authors: rubin jb. Trends Pharmacol Sci. 2011 Jun;32(6):337-44. doi: 10.1016/j.tips.2011.02.015. Epub 2011 Mar 28. Trends Pharmacol Sci. 2011. PMID: 21450351 Free PMC article.

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