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Page 1
Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma.
Barone A, Sengupta R, Warrington NM, Smith E, Wen PY, Brekken RA, Romagnoli B, Douglas G, Chevalier E, Bauer MP, Dembowsky K, Piwnica-Worms D, Rubin JB. Barone A, et al. Among authors: dembowsky k. Oncotarget. 2014 Oct 30;5(20):9811-22. doi: 10.18632/oncotarget.2443. Oncotarget. 2014. PMID: 25238146 Free PMC article.
CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.
Xiang J, Hurchla MA, Fontana F, Su X, Amend SR, Esser AK, Douglas GJ, Mudalagiriyappa C, Luker KE, Pluard T, Ademuyiwa FO, Romagnoli B, Tuffin G, Chevalier E, Luker GD, Bauer M, Zimmermann J, Aft RL, Dembowsky K, Weilbaecher KN. Xiang J, et al. Among authors: dembowsky k. Mol Cancer Ther. 2015 Nov;14(11):2473-85. doi: 10.1158/1535-7163.MCT-15-0252. Epub 2015 Aug 12. Mol Cancer Ther. 2015. PMID: 26269605 Free PMC article.
Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti-Vascular Endothelial Growth Factor Therapy-Induced Glioma Dissemination.
Gagner JP, Sarfraz Y, Ortenzi V, Alotaibi FM, Chiriboga LA, Tayyib AT, Douglas GJ, Chevalier E, Romagnoli B, Tuffin G, Schmitt M, Lemercier G, Dembowsky K, Zagzag D. Gagner JP, et al. Among authors: dembowsky k. Am J Pathol. 2017 Sep;187(9):2080-2094. doi: 10.1016/j.ajpath.2017.04.020. Epub 2017 Jul 20. Am J Pathol. 2017. PMID: 28734730 Free PMC article.
C-X-C Motif Chemokine Receptor 4 Blockade Promotes Tissue Repair After Myocardial Infarction by Enhancing Regulatory T Cell Mobilization and Immune-Regulatory Function.
Wang Y, Dembowsky K, Chevalier E, Stüve P, Korf-Klingebiel M, Lochner M, Napp LC, Frank H, Brinkmann E, Kanwischer A, Bauersachs J, Gyöngyösi M, Sparwasser T, Wollert KC. Wang Y, et al. Among authors: dembowsky k. Circulation. 2019 Apr 9;139(15):1798-1812. doi: 10.1161/CIRCULATIONAHA.118.036053. Circulation. 2019. PMID: 30696265 Free PMC article.
Continuous blockade of CXCR4 results in dramatic mobilization and expansion of hematopoietic stem and progenitor cells.
Karpova D, Ritchey JK, Holt MS, Abou-Ezzi G, Monlish D, Batoon L, Millard S, Spohn G, Wiercinska E, Chendamarai E, Yang W, Christ S, Gehrs L, Schuettpelz LG, Dembowsky K, Pettit AR, Rettig MP, Bonig H, DiPersio JF. Karpova D, et al. Among authors: dembowsky k. Blood. 2017 May 25;129(21):2939-2949. doi: 10.1182/blood-2016-10-746909. Epub 2017 Apr 11. Blood. 2017. PMID: 28400375 Free PMC article.
Cardiomyocyte cell cycle activation ameliorates fibrosis in the atrium.
Nakajima H, Nakajima HO, Dembowsky K, Pasumarthi KB, Field LJ. Nakajima H, et al. Among authors: dembowsky k. Circ Res. 2006 Jan 6;98(1):141-8. doi: 10.1161/01.RES.0000197783.70106.4a. Epub 2005 Nov 23. Circ Res. 2006. PMID: 16306446 Free PMC article.
Circulating tumor cells as a biomarker for response to therapy in multiple myeloma patients treated within the GMMG-MM5 trial.
Huhn S, Weinhold N, Nickel J, Pritsch M, Hielscher T, Hummel M, Bertsch U, Huegle-Doerr B, Vogel M, Angermund R, Hänel M, Salwender HJ, Weisel K, Dürig J, Görner M, Kirchner H, Peter N, Graeven U, Lordick F, Hoffmann M, Reimer P, Blau IW, Jauch A, Dembowsky K, Möhler T, Wuchter P, Goldschmidt H. Huhn S, et al. Among authors: dembowsky k. Bone Marrow Transplant. 2017 Aug;52(8):1194-1198. doi: 10.1038/bmt.2017.91. Epub 2017 May 15. Bone Marrow Transplant. 2017. PMID: 28504661 Free PMC article. Clinical Trial. No abstract available.
45 results