Ginther C - Search Results

1

KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition.

Hamidi H, Lu M, Chau K, Anderson L, Fejzo M, Ginther C, Linnartz R, Zubel A, Slamon DJ, Finn RS. Hamidi H, et al. Among authors: ginther c. Br J Cancer. 2014 Oct 28;111(9):1788-801. doi: 10.1038/bjc.2014.475. Epub 2014 Aug 28. Br J Cancer. 2014. PMID: 25167228 Free PMC article.

2

Identification of common predictive markers of in vitro response to the Mek inhibitor selumetinib (AZD6244; ARRY-142886) in human breast cancer and non-small cell lung cancer cell lines.

Garon EB, Finn RS, Hosmer W, Dering J, Ginther C, Adhami S, Kamranpour N, Pitts S, Desai A, Elashoff D, French T, Smith P, Slamon DJ. Garon EB, et al. Among authors: ginther c. Mol Cancer Ther. 2010 Jul;9(7):1985-94. doi: 10.1158/1535-7163.MCT-10-0037. Epub 2010 Jun 29. Mol Cancer Ther. 2010. PMID: 20587667 Free PMC article.

3

Molecular subtype and response to dasatinib, an Src/Abl small molecule kinase inhibitor, in hepatocellular carcinoma cell lines in vitro.

Finn RS, Aleshin A, Dering J, Yang P, Ginther C, Desai A, Zhao D, von Euw E, Busuttil RW, Slamon DJ. Finn RS, et al. Among authors: ginther c. Hepatology. 2013 May;57(5):1838-46. doi: 10.1002/hep.26223. Epub 2013 Apr 1. Hepatology. 2013. PMID: 23299860

4

AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53.

Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS. Kalous O, et al. Among authors: ginther c. Breast Cancer Res Treat. 2013 Oct;141(3):397-408. doi: 10.1007/s10549-013-2702-z. Epub 2013 Oct 5. Breast Cancer Res Treat. 2013. PMID: 24091768

5

Activity of the multikinase inhibitor dasatinib against ovarian cancer cells.

Konecny GE, Glas R, Dering J, Manivong K, Qi J, Finn RS, Yang GR, Hong KL, Ginther C, Winterhoff B, Gao G, Brugge J, Slamon DJ. Konecny GE, et al. Among authors: ginther c. Br J Cancer. 2009 Nov 17;101(10):1699-708. doi: 10.1038/sj.bjc.6605381. Epub 2009 Oct 27. Br J Cancer. 2009. PMID: 19861960 Free PMC article.

6

Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro.

Finn RS, Dering J, Ginther C, Wilson CA, Glaspy P, Tchekmedyian N, Slamon DJ. Finn RS, et al. Among authors: ginther c. Breast Cancer Res Treat. 2007 Nov;105(3):319-26. doi: 10.1007/s10549-006-9463-x. Epub 2007 Feb 1. Breast Cancer Res Treat. 2007. PMID: 17268817

7

Comprehensive analysis of 20q13 genes in ovarian cancer identifies ADRM1 as amplification target.

Fejzo MS, Dering J, Ginther C, Anderson L, Ramos L, Walsh C, Karlan B, Slamon DJ. Fejzo MS, et al. Among authors: ginther c. Genes Chromosomes Cancer. 2008 Oct;47(10):873-83. doi: 10.1002/gcc.20592. Genes Chromosomes Cancer. 2008. PMID: 18615678

8

Knockdown of ovarian cancer amplification target ADRM1 leads to downregulation of GIPC1 and upregulation of RECK.

Fejzo MS, Ginther C, Dering J, Anderson L, Venkatesan N, Konecny G, Karlan B, Slamon DJ. Fejzo MS, et al. Among authors: ginther c. Genes Chromosomes Cancer. 2011 Jun;50(6):434-41. doi: 10.1002/gcc.20868. Epub 2011 Mar 22. Genes Chromosomes Cancer. 2011. PMID: 21432940

9

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro.

Finn RS, Dering J, Conklin D, Kalous O, Cohen DJ, Desai AJ, Ginther C, Atefi M, Chen I, Fowst C, Los G, Slamon DJ. Finn RS, et al. Among authors: ginther c. Breast Cancer Res. 2009;11(5):R77. doi: 10.1186/bcr2419. Breast Cancer Res. 2009. PMID: 19874578 Free PMC article.

10

Periostin promotes ovarian cancer angiogenesis and metastasis.

Zhu M, Fejzo MS, Anderson L, Dering J, Ginther C, Ramos L, Gasson JC, Karlan BY, Slamon DJ. Zhu M, et al. Among authors: ginther c. Gynecol Oncol. 2010 Nov;119(2):337-44. doi: 10.1016/j.ygyno.2010.07.008. Epub 2010 Aug 4. Gynecol Oncol. 2010. PMID: 20688362

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