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Page 1
Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques.
Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, Nason MC, Montefiori D, Moldt B, Poignard P, Diskin R, Bjorkman PJ, Eckhaus MA, Klein F, Mouquet H, Cetrulo Lorenzi JC, Gazumyan A, Burton DR, Nussenzweig MC, Martin MA, Nishimura Y. Shingai M, et al. Among authors: cetrulo lorenzi jc. J Exp Med. 2014 Sep 22;211(10):2061-74. doi: 10.1084/jem.20132494. Epub 2014 Aug 25. J Exp Med. 2014. PMID: 25155019 Free PMC article.
A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch.
Wang Z, Barnes CO, Gautam R, Cetrulo Lorenzi JC, Mayer CT, Oliveira TY, Ramos V, Cipolla M, Gordon KM, Gristick HB, West AP, Nishimura Y, Raina H, Seaman MS, Gazumyan A, Martin M, Bjorkman PJ, Nussenzweig MC, Escolano A. Wang Z, et al. Among authors: cetrulo lorenzi jc. Elife. 2020 Oct 21;9:e61991. doi: 10.7554/eLife.61991. Elife. 2020. PMID: 33084569 Free PMC article.
A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Barnes CO, Schoofs T, Gnanapragasam PNP, Golijanin J, Huey-Tubman KE, Gruell H, Schommers P, Suh-Toma N, Lee YE, Cetrulo Lorenzi JC, Piechocka-Trocha A, Scheid JF, West AP Jr, Walker BD, Seaman MS, Klein F, Nussenzweig MC, Bjorkman PJ. Barnes CO, et al. Among authors: cetrulo lorenzi jc. Sci Adv. 2022 Aug 12;8(32):eabp8155. doi: 10.1126/sciadv.abp8155. Epub 2022 Aug 12. Sci Adv. 2022. PMID: 35960796 Free PMC article.
Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies.
Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR, Koranda N, Gristick HB, Gaebler C, Muecksch F, Cetrulo Lorenzi JC, Finkin S, Hagglof T, Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey M, Robbiani DF, Nussenzweig MC, Bjorkman PJ. Barnes CO, et al. Among authors: cetrulo lorenzi jc. bioRxiv [Preprint]. 2020 May 29:2020.05.28.121533. doi: 10.1101/2020.05.28.121533. bioRxiv. 2020. Update in: Cell. 2020 Aug 20;182(4):828-842.e16. doi: 10.1016/j.cell.2020.06.025. PMID: 32577645 Free PMC article. Updated. Preprint.
Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants.
Xu J, Xu K, Jung S, Conte A, Lieberman J, Muecksch F, Cetrulo Lorenzi JC, Park S, Wang Z, Tessarollo L, Bylund T, Chuang GY, Olia AS, Stephens T, Teng IT, Tsybovsky Y, Zhou T, Hatziioannou T, Bieniasz PD, Nussenzweig MC, Kwong PD, Casellas R. Xu J, et al. Among authors: cetrulo lorenzi jc. bioRxiv [Preprint]. 2021 Mar 4:2021.03.04.433768. doi: 10.1101/2021.03.04.433768. bioRxiv. 2021. Update in: Nature. 2021 Jul;595(7866):278-282. doi: 10.1038/s41586-021-03676-z. PMID: 33688659 Free PMC article. Updated. Preprint.
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
Ruhrmann S, Ewing E, Piket E, Kular L, Cetrulo Lorenzi JC, Fernandes SJ, Morikawa H, Aeinehband S, Sayols-Baixeras S, Aslibekyan S, Absher DM, Arnett DK, Tegner J, Gomez-Cabrero D, Piehl F, Jagodic M. Ruhrmann S, et al. Among authors: cetrulo lorenzi jc. Mult Scler. 2018 Sep;24(10):1288-1300. doi: 10.1177/1352458517721356. Epub 2017 Aug 2. Mult Scler. 2018. PMID: 28766461 Free PMC article.