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Page 1
Intravascular delivery of an MK2 inhibitory peptide to prevent restenosis after angioplasty.
Tierney JW, Francisco RP, Yu F, Ma J, Cheung-Flynn J, Keech MC, D'Arcy R, Shah VM, Kittel AR, Chang DJ, McCune JT, Bezold MG, Aligwekwe AN, Cook RS, Beckman JA, Brophy CM, Duvall CL. Tierney JW, et al. Among authors: cook rs. Biomaterials. 2025 Feb;313:122767. doi: 10.1016/j.biomaterials.2024.122767. Epub 2024 Aug 23. Biomaterials. 2025. PMID: 39216327 Free article.
Polymeric Micellar Nanoparticles Enable Image-guided Drug Delivery in Solid Tumors.
Uddin J, Oltman CG, Lo JH, Gupta MK, Werfel TA, Mohyuddin M, Nazmin F, Rahman S, Crews BC, Kingsley PJ, Marnett LJ, Duvall CL, Cook RS. Uddin J, et al. Among authors: cook rs. bioRxiv [Preprint]. 2024 Jun 10:2024.06.07.598019. doi: 10.1101/2024.06.07.598019. bioRxiv. 2024. PMID: 38915607 Free PMC article. Preprint.
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy.
Hoogenboezem EN, Patel SS, Lo JH, Cavnar AB, Babb LM, Francini N, Gbur EF, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL. Hoogenboezem EN, et al. Among authors: cook rs. Nat Commun. 2024 Feb 21;15(1):1581. doi: 10.1038/s41467-024-45609-0. Nat Commun. 2024. PMID: 38383524 Free PMC article.
Albumin-binding RNAi Conjugate for Carrier Free Treatment of Arthritis.
Colazo JM, Hoogenboezem EN, Keech MC, Francini N, Shah V, Yu F, Lo JH, Sorets AG, McCune JT, Cho H, DeJulius CR, Michell DL, Maerz T, Vickers KC, Gibson-Corley KN, Hasty KA, Crofford L, Cook RS, Duvall CL. Colazo JM, et al. Among authors: cook rs. bioRxiv [Preprint]. 2023 Dec 28:2023.05.31.542971. doi: 10.1101/2023.05.31.542971. bioRxiv. 2023. PMID: 37333210 Free PMC article. Preprint.
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing.
Patel SS, Hoogenboezem EN, Yu F, DeJulius CR, Fletcher RB, Sorets AG, Cherry FK, Lo JH, Bezold MG, Francini N, d'Arcy R, Brasuell JE, Cook RS, Duvall CL. Patel SS, et al. Among authors: cook rs. Biomaterials. 2023 Jun;297:122098. doi: 10.1016/j.biomaterials.2023.122098. Epub 2023 Mar 28. Biomaterials. 2023. PMID: 37031547 Free PMC article.
Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy.
Hoogenboezem EN, Patel SS, Cavnar AB, Lo JH, Babb LM, Francini N, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL. Hoogenboezem EN, et al. Among authors: cook rs. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528574. doi: 10.1101/2023.02.14.528574. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 21;15(1):1581. doi: 10.1038/s41467-024-45609-0. PMID: 36824780 Free PMC article. Updated. Preprint.
Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer.
Hanna A, Nixon MJ, Estrada MV, Sanchez V, Sheng Q, Opalenik SR, Toren AL, Bauer J, Owens P, Mason FM, Cook RS, Sanders ME, Arteaga CL, Balko JM. Hanna A, et al. Among authors: cook rs. Breast Cancer Res. 2022 Jul 18;24(1):51. doi: 10.1186/s13058-022-01542-y. Breast Cancer Res. 2022. PMID: 35850776 Free PMC article.
MLL3 is a de novo cause of endocrine therapy resistance.
Stauffer KM, Elion DL, Cook RS, Stricker T. Stauffer KM, et al. Among authors: cook rs. Cancer Med. 2021 Nov;10(21):7692-7711. doi: 10.1002/cam4.4285. Epub 2021 Sep 28. Cancer Med. 2021. PMID: 34581028 Free PMC article.
119 results