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19-Hydroxyeicosatetraenoic acid analogs: Antagonism of 20-hydroxyeicosatetraenoic acid-induced vascular sensitization and hypertension.
Dakarapu R, Errabelli R, Manthati VL, Michael Adebesin A, Barma DK, Barma D, Garcia V, Zhang F, Laniado Schwartzman M, Falck JR. Dakarapu R, et al. Among authors: manthati vl. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126616. doi: 10.1016/j.bmcl.2019.08.020. Epub 2019 Aug 13. Bioorg Med Chem Lett. 2019. PMID: 31439380 Free PMC article.
Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγ.
Kim DH, Vanella L, Inoue K, Burgess A, Gotlinger K, Manthati VL, Koduru SR, Zeldin DC, Falck JR, Schwartzman ML, Abraham NG. Kim DH, et al. Among authors: manthati vl. Stem Cells Dev. 2010 Dec;19(12):1863-73. doi: 10.1089/scd.2010.0098. Epub 2010 Oct 9. Stem Cells Dev. 2010. PMID: 20412023 Free PMC article.
Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.
Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Gangadhariah MH, et al. Among authors: manthati vl. J Am Soc Nephrol. 2015 Mar;26(3):597-610. doi: 10.1681/ASN.2013090980. Epub 2014 Jul 28. J Am Soc Nephrol. 2015. PMID: 25071086 Free PMC article.
Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions.
Imig JD, Elmarakby A, Nithipatikom K, Wei S, Capdevila JH, Tuniki VR, Sangras B, Anjaiah S, Manthati VL, Sudarshan Reddy D, Falck JR. Imig JD, et al. Among authors: manthati vl. Front Physiol. 2010 Dec 3;1:157. doi: 10.3389/fphys.2010.00157. eCollection 2010. Front Physiol. 2010. PMID: 21423396 Free PMC article.
Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides.
Gao N, Shang J, Huynh D, Manthati VL, Arias C, Harding HP, Kaufman RJ, Mohr I, Ron D, Falck JR, Lehrman MA. Gao N, et al. Among authors: manthati vl. Mol Biol Cell. 2011 Sep;22(17):2994-3009. doi: 10.1091/mbc.E11-04-0286. Epub 2011 Jul 7. Mol Biol Cell. 2011. PMID: 21737679 Free PMC article.
29 results