Haley J - Search Results

1

Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance.

Haley J, White FM. Haley J, et al. Biochem Soc Trans. 2014 Aug;42(4):758-64. doi: 10.1042/BST20140038. Biochem Soc Trans. 2014. PMID: 25109954 Review.

2

SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC.

Ruiz CF, Montal ED, Haley JA, Bott AJ, Haley JD. Ruiz CF, et al. Among authors: haley ja, haley jd. FASEB J. 2020 Aug;34(8):10574-10589. doi: 10.1096/fj.202000052R. Epub 2020 Jun 22. FASEB J. 2020. PMID: 32568455 Free PMC article.

3

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer.

Singh A, Ruiz C, Bhalla K, Haley JA, Li QK, Acquaah-Mensah G, Montal E, Sudini KR, Skoulidis F, Wistuba II, Papadimitrakopoulou V, Heymach JV, Boros LG, Gabrielson E, Carretero J, Wong KK, Haley JD, Biswal S, Girnun GD. Singh A, et al. Among authors: haley ja, haley jd. FASEB J. 2018 Jun 15;32(12):fj201800204. doi: 10.1096/fj.201800204. Online ahead of print. FASEB J. 2018. PMID: 29906244 Free PMC article.

These studies highlight the potential to target mutant Kras tumors by taking advantage of the lipogenic phenotype induced by mutant Kras.-Singh, A., Ruiz, C., Bhalla, K., Haley, J. A., Li, Q. K., Acquaah-Mensah, G., Montal, E., Sudini, K. R., Skoulidis, F., Wistuba, …

These studies highlight the potential to target mutant Kras tumors by taking advantage of the lipogenic phenotype induced by mutant Kras.-Si …

4

Altered Transcriptional Control Networks with Trans-Differentiation of Isogenic Mutant-KRas NSCLC Models.

Haley JA, Haughney E, Ullman E, Bean J, Haley JD, Fink MY. Haley JA, et al. Among authors: haley jd. Front Oncol. 2014 Dec 8;4:344. doi: 10.3389/fonc.2014.00344. eCollection 2014. Front Oncol. 2014. PMID: 25538889 Free PMC article.

5

Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer.

Haley JA, Ruiz CF, Montal ED, Wang D, Haley JD, Girnun GD. Haley JA, et al. Cancers (Basel). 2019 Oct 2;11(10):1488. doi: 10.3390/cancers11101488. Cancers (Basel). 2019. PMID: 31581742 Free PMC article.

6

Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer.

Montal ED, Bhalla K, Dewi RE, Ruiz CF, Haley JA, Ropell AE, Gordon C, Haley JD, Girnun GD. Montal ED, et al. Cancer Metab. 2019 Aug 1;7:8. doi: 10.1186/s40170-019-0199-6. eCollection 2019. Cancer Metab. 2019. PMID: 31388420 Free PMC article.

7

The doxorubicin-induced cell motility network is under the control of the ceramide-activated protein phosphatase 1 alpha.

Canals D, Salamone S, Santacreu BJ, Aguilar D, Hernandez-Corbacho MJ, Ostermeyer-Fay AG, Greene M, Nemeth E, Haley JD, Obeid LM, Hannun YA. Canals D, et al. FASEB J. 2021 Mar;35(3):e21396. doi: 10.1096/fj.202002427R. FASEB J. 2021. PMID: 33583073 Free PMC article.

8

PKCα is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation.

Salama MF, Liu M, Clarke CJ, Espaillat MP, Haley JD, Jin T, Wang D, Obeid LM, Hannun YA. Salama MF, et al. Among authors: haley jd. Oncogene. 2019 Nov;38(48):7311-7328. doi: 10.1038/s41388-019-0950-z. Epub 2019 Aug 16. Oncogene. 2019. PMID: 31420605 Free PMC article.

9

Comparative gene co-expression network analysis of epithelial to mesenchymal transition reveals lung cancer progression stages.

Wang D, Haley JD, Thompson P. Wang D, et al. BMC Cancer. 2017 Dec 6;17(1):830. doi: 10.1186/s12885-017-3832-1. BMC Cancer. 2017. PMID: 29212455 Free PMC article.

10

Inducible expression of TGFβ, snail and Zeb1 recapitulates EMT in vitro and in vivo in a NSCLC model.

Argast GM, Krueger JS, Thomson S, Sujka-Kwok I, Carey K, Silva S, O'Connor M, Mercado P, Mulford IJ, Young GD, Sennello R, Wild R, Pachter JA, Kan JL, Haley J, Rosenfeld-Franklin M, Epstein DM. Argast GM, et al. Among authors: haley j. Clin Exp Metastasis. 2011 Oct;28(7):593-614. doi: 10.1007/s10585-011-9394-8. Epub 2011 Jun 4. Clin Exp Metastasis. 2011. PMID: 21643654

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