Woutersen RA - Search Results

1

Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations.

van de Pas NC, Rullmann JA, Woutersen RA, van Ommen B, Rietjens IM, de Graaf AA. van de Pas NC, et al. Among authors: woutersen ra. J Pharmacokinet Pharmacodyn. 2014 Aug;41(4):351-62. doi: 10.1007/s10928-014-9369-x. Epub 2014 Aug 9. J Pharmacokinet Pharmacodyn. 2014. PMID: 25106950

2

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes.

van de Pas NC, Soffers AE, Freidig AP, van Ommen B, Woutersen RA, Rietjens IM, de Graaf AA. van de Pas NC, et al. Among authors: woutersen ra. Biochim Biophys Acta. 2010 Jun;1801(6):646-54. doi: 10.1016/j.bbalip.2010.02.009. Epub 2010 Feb 20. Biochim Biophys Acta. 2010. PMID: 20176131

3

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse.

van de Pas NC, Woutersen RA, van Ommen B, Rietjens IM, de Graaf AA. van de Pas NC, et al. Among authors: woutersen ra. Biochim Biophys Acta. 2011 May;1811(5):333-42. doi: 10.1016/j.bbalip.2011.02.002. Epub 2011 Feb 12. Biochim Biophys Acta. 2011. PMID: 21320632

4

A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans.

van de Pas NC, Woutersen RA, van Ommen B, Rietjens IM, de Graaf AA. van de Pas NC, et al. Among authors: woutersen ra. J Lipid Res. 2012 Dec;53(12):2734-46. doi: 10.1194/jlr.M031930. Epub 2012 Sep 29. J Lipid Res. 2012. PMID: 23024287 Free PMC article.

5

Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols.

Strikwold M, Spenkelink B, de Haan LHJ, Woutersen RA, Punt A, Rietjens IMCM. Strikwold M, et al. Among authors: woutersen ra. Arch Toxicol. 2017 May;91(5):2119-2133. doi: 10.1007/s00204-016-1881-x. Epub 2016 Nov 4. Arch Toxicol. 2017. PMID: 27815601 Free PMC article.

6

Development of a Combined In Vitro Physiologically Based Kinetic (PBK) and Monte Carlo Modelling Approach to Predict Interindividual Human Variation in Phenol-Induced Developmental Toxicity.

Strikwold M, Spenkelink B, Woutersen RA, Rietjens IMCM, Punt A. Strikwold M, et al. Among authors: woutersen ra. Toxicol Sci. 2017 Jun 1;157(2):365-376. doi: 10.1093/toxsci/kfx054. Toxicol Sci. 2017. PMID: 28498972

7

Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose-response curves for developmental toxicity of phenol in rat and human.

Strikwold M, Spenkelink B, Woutersen RA, Rietjens IM, Punt A. Strikwold M, et al. Among authors: woutersen ra. Arch Toxicol. 2013 Sep;87(9):1709-23. doi: 10.1007/s00204-013-1107-4. Epub 2013 Aug 14. Arch Toxicol. 2013. PMID: 23943240

8

Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2.

Dihal AA, Woutersen RA, van Ommen B, Rietjens IM, Stierum RH. Dihal AA, et al. Among authors: woutersen ra. Cancer Lett. 2006 Jul 18;238(2):248-59. doi: 10.1016/j.canlet.2005.07.007. Epub 2005 Aug 29. Cancer Lett. 2006. PMID: 16129554

9

The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man.

Louisse J, de Jong E, van de Sandt JJ, Blaauboer BJ, Woutersen RA, Piersma AH, Rietjens IM, Verwei M. Louisse J, et al. Among authors: woutersen ra. Toxicol Sci. 2010 Dec;118(2):470-84. doi: 10.1093/toxsci/kfq270. Epub 2010 Sep 10. Toxicol Sci. 2010. PMID: 20833708

10

Pathway and single gene analyses of inhibited Caco-2 differentiation by ascorbate-stabilized quercetin suggest enhancement of cellular processes associated with development of colon cancer.

Dihal AA, Tilburgs C, van Erk MJ, Rietjens IM, Woutersen RA, Stierum RH. Dihal AA, et al. Among authors: woutersen ra. Mol Nutr Food Res. 2007 Aug;51(8):1031-45. doi: 10.1002/mnfr.200600261. Mol Nutr Food Res. 2007. PMID: 17639512

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