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Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease.
Sassi C, Guerreiro R, Gibbs R, Ding J, Lupton MK, Troakes C, Al-Sarraj S, Niblock M, Gallo JM, Adnan J, Killick R, Brown KS, Medway C, Lord J, Turton J, Bras J; Alzheimer's Research UK Consortium; Morgan K, Powell JF, Singleton A, Hardy J. Sassi C, et al. Among authors: killick r. Neurobiol Aging. 2014 Dec;35(12):2881.e1-2881.e6. doi: 10.1016/j.neurobiolaging.2014.06.002. Epub 2014 Jun 16. Neurobiol Aging. 2014. PMID: 25104557 Free PMC article.
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, Al-Saraj S, Killick R, Pickering-Brown S, Moore P, Hollingworth P, Archer N, Foy C, Walter S, Lendon C, Iwatsubo T, Morris JC, Norton J, Mann D, Janssens B, Hardy J, O'Donovan M, Jones L, Williams J, Holmans P, Owen MJ, Grupe A, Powell J, van Hengel J, Goate A, Van Roy F, Lovestone S. Busby V, et al. Among authors: killick r. Neuromolecular Med. 2004;5(2):133-46. doi: 10.1385/NMM:5:2:133. Neuromolecular Med. 2004. PMID: 15075440
Plasma transthyretin as a candidate marker for Alzheimer's disease.
Velayudhan L, Killick R, Hye A, Kinsey A, Güntert A, Lynham S, Ward M, Leung R, Lourdusamy A, To AW, Powell J, Lovestone S. Velayudhan L, et al. Among authors: killick r. J Alzheimers Dis. 2012;28(2):369-75. doi: 10.3233/JAD-2011-110611. J Alzheimers Dis. 2012. PMID: 22002789 Free article.
Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.
Hamilton G, Killick R; Genetic and Environmental Risk for Alzheimer's Disease Consortium; Translational Genomics Research Institute Consortium; Lambert JC, Amouyel P; European Alzheimer Disease Initiative; Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R. Hamilton G, et al. Among authors: killick r. Neurobiol Aging. 2012 Aug;33(8):1848.e1-13. doi: 10.1016/j.neurobiolaging.2012.02.005. Epub 2012 Mar 8. Neurobiol Aging. 2012. PMID: 22405046 Free PMC article.
Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.
Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Curtis C, Breen G, Williams SC, Lovestone S, Spector TD, Dobson RJ. Kiddle SJ, et al. Among authors: killick r. Transl Psychiatry. 2015 Jun 16;5(6):e584. doi: 10.1038/tp.2015.78. Transl Psychiatry. 2015. PMID: 26080319 Free PMC article.
123 results