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TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.
Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, Lammich S, Molinuevo JL, Sánchez-Valle R, Antonell A, Ramirez A, Heneka MT, Sleegers K, van der Zee J, Martin JJ, Engelborghs S, Demirtas-Tatlidede A, Zetterberg H, Van Broeckhoven C, Gurvit H, Wyss-Coray T, Hardy J, Colonna M, Haass C. Kleinberger G, et al. Among authors: willem m. Sci Transl Med. 2014 Jul 2;6(243):243ra86. doi: 10.1126/scitranslmed.3009093. Sci Transl Med. 2014. PMID: 24990881
Maturation and pro-peptide cleavage of beta-secretase.
Capell A, Steiner H, Willem M, Kaiser H, Meyer C, Walter J, Lammich S, Multhaup G, Haass C. Capell A, et al. Among authors: willem m. J Biol Chem. 2000 Oct 6;275(40):30849-54. doi: 10.1074/jbc.M003202200. J Biol Chem. 2000. PMID: 10801872 Free article.
Phosphorylation regulates intracellular trafficking of beta-secretase.
Walter J, Fluhrer R, Hartung B, Willem M, Kaether C, Capell A, Lammich S, Multhaup G, Haass C. Walter J, et al. Among authors: willem m. J Biol Chem. 2001 May 4;276(18):14634-41. doi: 10.1074/jbc.M011116200. Epub 2001 Jan 29. J Biol Chem. 2001. PMID: 11278841 Free article.
A non-amyloidogenic function of BACE-2 in the secretory pathway.
Fluhrer R, Capell A, Westmeyer G, Willem M, Hartung B, Condron MM, Teplow DB, Haass C, Walter J. Fluhrer R, et al. Among authors: willem m. J Neurochem. 2002 Jun;81(5):1011-20. doi: 10.1046/j.1471-4159.2002.00908.x. J Neurochem. 2002. PMID: 12065613 Free article.
Dimerization of beta-site beta-amyloid precursor protein-cleaving enzyme.
Westmeyer GG, Willem M, Lichtenthaler SF, Lurman G, Multhaup G, Assfalg-Machleidt I, Reiss K, Saftig P, Haass C. Westmeyer GG, et al. Among authors: willem m. J Biol Chem. 2004 Dec 17;279(51):53205-12. doi: 10.1074/jbc.M410378200. Epub 2004 Oct 12. J Biol Chem. 2004. PMID: 15485862 Free article.
80 results