Chen G - Search Results

1

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer.

Qi X, Xie C, Hou S, Li G, Yin N, Dong L, Lepp A, Chesnik MA, Mirza SP, Szabo A, Tsai S, Basir Z, Wu S, Chen G. Qi X, et al. Among authors: chen g. Oncotarget. 2014 Jun 30;5(12):4269-82. doi: 10.18632/oncotarget.2001. Oncotarget. 2014. PMID: 24962213 Free PMC article.

2

The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition.

Qi X, Pramanik R, Wang J, Schultz RM, Maitra RK, Han J, DeLuca HF, Chen G. Qi X, et al. Among authors: chen g. J Biol Chem. 2002 Jul 19;277(29):25884-92. doi: 10.1074/jbc.M203039200. Epub 2002 Apr 30. J Biol Chem. 2002. PMID: 11983707 Free article.

3

p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity.

Pramanik R, Qi X, Borowicz S, Choubey D, Schultz RM, Han J, Chen G. Pramanik R, et al. Among authors: chen g. J Biol Chem. 2003 Feb 14;278(7):4831-9. doi: 10.1074/jbc.M207732200. Epub 2002 Dec 9. J Biol Chem. 2003. PMID: 12475989 Free article.

4

Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells.

Qi X, Borowicz S, Pramanik R, Schultz RM, Han J, Chen G. Qi X, et al. Among authors: chen g. J Biol Chem. 2004 Feb 20;279(8):6769-77. doi: 10.1074/jbc.M311492200. Epub 2003 Nov 24. J Biol Chem. 2004. PMID: 14638681 Free article.

5

p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor.

Qi X, Tang J, Pramanik R, Schultz RM, Shirasawa S, Sasazuki T, Han J, Chen G. Qi X, et al. Among authors: chen g. J Biol Chem. 2004 May 21;279(21):22138-44. doi: 10.1074/jbc.M313964200. Epub 2004 Mar 22. J Biol Chem. 2004. PMID: 15037631 Free article.

Our previous work demonstrated the inhibitory activity of the p38 pathway in Ras proliferative signaling in experimental NIH 3T3 cells (Chen, G., Hitomi, M., Han, J., and Stacey, D. W. (2000) J. Biol. Chem. 275, 38973-38980). ...

Our previous work demonstrated the inhibitory activity of the p38 pathway in Ras proliferative signaling in experimental NIH 3T3 cells (C …

6

Essential role of p38gamma in K-Ras transformation independent of phosphorylation.

Tang J, Qi X, Mercola D, Han J, Chen G. Tang J, et al. Among authors: chen g. J Biol Chem. 2005 Jun 24;280(25):23910-7. doi: 10.1074/jbc.M500699200. Epub 2005 Apr 25. J Biol Chem. 2005. PMID: 15851477 Free PMC article.

Whereas the ERK MAPK pathway is required for Ras transformation, our previous works established that the p38 activity is inhibitory to Ras signaling in both experimental and ras-mutated cancer cells (Chen, G., Hitomi, M., Han, J., and Stacey, D. W. (2000) J. Biol. C …

Whereas the ERK MAPK pathway is required for Ras transformation, our previous works established that the p38 activity is inhibitory to Ras s …

7

p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion.

Qi X, Tang J, Loesch M, Pohl N, Alkan S, Chen G. Qi X, et al. Among authors: chen g. Cancer Res. 2006 Aug 1;66(15):7540-7. doi: 10.1158/0008-5472.CAN-05-4639. Cancer Res. 2006. PMID: 16885352 Free PMC article.

8

Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity.

Li QP, Qi X, Pramanik R, Pohl NM, Loesch M, Chen G. Li QP, et al. Among authors: chen g. J Biol Chem. 2007 Jan 19;282(3):1544-51. doi: 10.1074/jbc.M604052200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121851 Free article.

M., Maitra, R. K., Han, J., DeLuca, H. F., and Chen, G. (2002) J. Biol. Chem. 277, 25884-25892) and VDR inhibits cell death in response to p38 MAPK activation (Qi, X., Tang, J., Pramanik, R., Schultz, R. M., Shirasawa, S., Sasazuki, T., Han, J., and Chen, …

M., Maitra, R. K., Han, J., DeLuca, H. F., and Chen, G. (2002) J. Biol. Chem. 277, 25884-25892) and VDR inhibits cell death in …

9

p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response.

Qi X, Pohl NM, Loesch M, Hou S, Li R, Qin JZ, Cuenda A, Chen G. Qi X, et al. Among authors: chen g. J Biol Chem. 2007 Oct 26;282(43):31398-408. doi: 10.1074/jbc.M703857200. Epub 2007 Aug 27. J Biol Chem. 2007. PMID: 17724032 Free article.

10

p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9.

Loesch M, Zhi HY, Hou SW, Qi XM, Li RS, Basir Z, Iftner T, Cuenda A, Chen G. Loesch M, et al. Among authors: chen g. J Biol Chem. 2010 May 14;285(20):15149-15158. doi: 10.1074/jbc.M110.105429. Epub 2010 Mar 15. J Biol Chem. 2010. PMID: 20231272 Free PMC article.

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