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PP2A inhibition overcomes acquired resistance to HER2 targeted therapy.
McDermott MS, Browne BC, Conlon NT, O'Brien NA, Slamon DJ, Henry M, Meleady P, Clynes M, Dowling P, Crown J, O'Donovan N. McDermott MS, et al. Among authors: browne bc. Mol Cancer. 2014 Jun 24;13:157. doi: 10.1186/1476-4598-13-157. Mol Cancer. 2014. PMID: 24958351 Free PMC article.
HER-2 signaling and inhibition in breast cancer.
Browne BC, O'Brien N, Duffy MJ, Crown J, O'Donovan N. Browne BC, et al. Curr Cancer Drug Targets. 2009 May;9(3):419-38. doi: 10.2174/156800909788166484. Curr Cancer Drug Targets. 2009. PMID: 19442060 Review.
Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL.
Eustace AJ, Conlon NT, McDermott MSJ, Browne BC, O'Leary P, Holmes FA, Espina V, Liotta LA, O'Shaughnessy J, Gallagher C, O'Driscoll L, Rani S, Madden SF, O'Brien NA, Ginther C, Slamon D, Walsh N, Gallagher WM, Zagozdzon R, Watson WR, O'Donovan N, Crown J. Eustace AJ, et al. Among authors: browne bc. BMC Cancer. 2018 Oct 11;18(1):965. doi: 10.1186/s12885-018-4852-1. BMC Cancer. 2018. PMID: 30305055 Free PMC article.
21 results