McMahon M - Search Results

1

Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond.

Holderfield M, Deuker MM, McCormick F, McMahon M. Holderfield M, et al. Among authors: mcmahon m. Nat Rev Cancer. 2014 Jul;14(7):455-67. doi: 10.1038/nrc3760. Nat Rev Cancer. 2014. PMID: 24957944 Free PMC article. Review.

2

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK.

Minden A, Lin A, McMahon M, Lange-Carter C, Dérijard B, Davis RJ, Johnson GL, Karin M. Minden A, et al. Among authors: mcmahon m. Science. 1994 Dec 9;266(5191):1719-23. doi: 10.1126/science.7992057. Science. 1994. PMID: 7992057

3

Regulation of mitogen-activated protein kinase phosphatase-1 expression by extracellular signal-related kinase-dependent and Ca2+-dependent signal pathways in Rat-1 cells.

Cook SJ, Beltman J, Cadwallader KA, McMahon M, McCormick F. Cook SJ, et al. Among authors: mcmahon m. J Biol Chem. 1997 May 16;272(20):13309-19. doi: 10.1074/jbc.272.20.13309. J Biol Chem. 1997. PMID: 9148952 Free article.

4

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, Sasazuki T, McMahon M, Oren M, McCormick F. Ries S, et al. Among authors: mcmahon m. Cell. 2000 Oct 13;103(2):321-30. doi: 10.1016/s0092-8674(00)00123-9. Cell. 2000. PMID: 11057904 Free article.

5

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.

Woods D, Cherwinski H, Venetsanakos E, Bhat A, Gysin S, Humbert M, Bray PF, Saylor VL, McMahon M. Woods D, et al. Among authors: mcmahon m. Mol Cell Biol. 2001 May;21(9):3192-205. doi: 10.1128/MCB.21.9.3192-3205.2001. Mol Cell Biol. 2001. PMID: 11287623 Free PMC article.

6

Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.

Anders M, Christian C, McMahon M, McCormick F, Korn WM. Anders M, et al. Among authors: mcmahon m. Cancer Res. 2003 May 1;63(9):2088-95. Cancer Res. 2003. PMID: 12727824

7

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT.

Mirza AM, Gysin S, Malek N, Nakayama K, Roberts JM, McMahon M. Mirza AM, et al. Among authors: mcmahon m. Mol Cell Biol. 2004 Dec;24(24):10868-81. doi: 10.1128/MCB.24.24.10868-10881.2004. Mol Cell Biol. 2004. PMID: 15572689 Free PMC article.

8

Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.

Gysin S, Lee SH, Dean NM, McMahon M. Gysin S, et al. Among authors: mcmahon m. Cancer Res. 2005 Jun 1;65(11):4870-80. doi: 10.1158/0008-5472.CAN-04-2848. Cancer Res. 2005. PMID: 15930308

9

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors.

Dankort D, Filenova E, Collado M, Serrano M, Jones K, McMahon M. Dankort D, et al. Among authors: mcmahon m. Genes Dev. 2007 Feb 15;21(4):379-84. doi: 10.1101/gad.1516407. Epub 2007 Feb 13. Genes Dev. 2007. PMID: 17299132 Free PMC article.

10

Oncogenic BRAF(V600E) inhibits BIM expression to promote melanoma cell survival.

Cartlidge RA, Thomas GR, Cagnol S, Jong KA, Molton SA, Finch AJ, McMahon M. Cartlidge RA, et al. Among authors: mcmahon m. Pigment Cell Melanoma Res. 2008 Oct;21(5):534-44. doi: 10.1111/j.1755-148X.2008.00491.x. Epub 2007 Jul 28. Pigment Cell Melanoma Res. 2008. PMID: 18715233 Free PMC article.

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