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Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression.
Hote PT, Sahoo R, Jani TS, Ghare SS, Chen T, Joshi-Barve S, McClain CJ, Barve SS. Hote PT, et al. Among authors: ghare ss. J Nutr Biochem. 2008 Jun;19(6):384-91. doi: 10.1016/j.jnutbio.2007.05.010. Epub 2007 Sep 14. J Nutr Biochem. 2008. PMID: 17869084 Free PMC article.
S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway.
Gobejishvili L, Avila DV, Barker DF, Ghare S, Henderson D, Brock GN, Kirpich IA, Joshi-Barve S, Mokshagundam SP, McClain CJ, Barve S. Gobejishvili L, et al. Among authors: ghare s. J Pharmacol Exp Ther. 2011 May;337(2):433-43. doi: 10.1124/jpet.110.174268. Epub 2011 Jan 25. J Pharmacol Exp Ther. 2011. PMID: 21266552 Free PMC article.
Binge alcohol-induced microvesicular liver steatosis and injury are associated with down-regulation of hepatic Hdac 1, 7, 9, 10, 11 and up-regulation of Hdac 3.
Kirpich I, Ghare S, Zhang J, Gobejishvili L, Kharebava G, Barve SJ, Barker D, Moghe A, McClain CJ, Barve S. Kirpich I, et al. Among authors: ghare s. Alcohol Clin Exp Res. 2012 Sep;36(9):1578-86. doi: 10.1111/j.1530-0277.2012.01751.x. Epub 2012 Feb 29. Alcohol Clin Exp Res. 2012. PMID: 22375794 Free PMC article.
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