Dubowchik GM - Search Results

1

Discovery of BMS-846372, a Potent and Orally Active Human CGRP Receptor Antagonist for the Treatment of Migraine.

Luo G, Chen L, Conway CM, Denton R, Keavy D, Gulianello M, Huang Y, Kostich W, Lentz KA, Mercer SE, Schartman R, Signor L, Browning M, Macor JE, Dubowchik GM. Luo G, et al. Among authors: dubowchik gm. ACS Med Chem Lett. 2012 Feb 27;3(4):337-41. doi: 10.1021/ml300021s. eCollection 2012 Apr 12. ACS Med Chem Lett. 2012. PMID: 24900474 Free PMC article.

2

Tetrahydroisoquinoline derivatives as melatonin MT2 receptor antagonists.

Karageorge GN, Bertenshaw S, Iben L, Xu C, Sarbin N, Gentile A, Dubowchik GM. Karageorge GN, et al. Among authors: dubowchik gm. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5881-4. doi: 10.1016/j.bmcl.2004.09.024. Bioorg Med Chem Lett. 2004. PMID: 15501061

3

Stereoselective synthesis of new conformationally restricted analogues of a potent CGRP receptor antagonist.

Zuev D, Michne JA, Huang H, Beno BR, Wu D, Gao Q, Torrente JR, Xu C, Conway CM, Macor JE, Dubowchik GM. Zuev D, et al. Among authors: dubowchik gm. Org Lett. 2005 Jun 9;7(12):2465-8. doi: 10.1021/ol0510062. Org Lett. 2005. PMID: 15932224

4

Synthesis and structure-activity relationship of imidazo[1,2-a]benzimidazoles as corticotropin-releasing factor 1 receptor antagonists.

Han X, Pin SS, Burris K, Fung LK, Huang S, Taber MT, Zhang J, Dubowchik GM. Han X, et al. Among authors: dubowchik gm. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4029-32. doi: 10.1016/j.bmcl.2005.06.028. Bioorg Med Chem Lett. 2005. PMID: 15982881

5

Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.

Han X, Michne JA, Pin SS, Burris KD, Balanda LA, Fung LK, Fiedler T, Browman KE, Taber MT, Zhang J, Dubowchik GM. Han X, et al. Among authors: dubowchik gm. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3870-3. doi: 10.1016/j.bmcl.2005.05.117. Bioorg Med Chem Lett. 2005. PMID: 15990298

6

Regioselective protection at N-2 and derivatization at C-3 of indazoles.

Luo G, Chen L, Dubowchik G. Luo G, et al. J Org Chem. 2006 Jul 7;71(14):5392-5. doi: 10.1021/jo060607j. J Org Chem. 2006. PMID: 16808535

7

An orally active corticotropin releasing factor 1 receptor antagonist from 8-aryl-1,3a,7,8-tetraaza-cyclopenta[a]indenes.

Han X, Civiello R, Pin SS, Burris K, Balanda LA, Knipe J, Ren S, Fiedler T, Browman KE, Macci R, Taber MT, Zhang J, Dubowchik GM. Han X, et al. Among authors: dubowchik gm. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2026-30. doi: 10.1016/j.bmcl.2007.01.008. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17258456

8

Discovery of (R)-4-(8-fluoro-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-(3-(7-methyl-1H-indazol-5-yl)-1-oxo-1-(4-(piperidin-1-yl)piperidin-1-yl)propan-2-yl)piperidine-1-carboxamide (BMS-694153): a potent antagonist of the human calcitonin gene-related peptide receptor for migraine with rapid and efficient intranasal exposure.

Degnan AP, Chaturvedula PV, Conway CM, Cook DA, Davis CD, Denton R, Han X, Macci R, Mathias NR, Moench P, Pin SS, Ren SX, Schartman R, Signor LJ, Thalody G, Widmann KA, Xu C, Macor JE, Dubowchik GM. Degnan AP, et al. Among authors: dubowchik gm. J Med Chem. 2008 Aug 28;51(16):4858-61. doi: 10.1021/jm800546t. Epub 2008 Jul 30. J Med Chem. 2008. PMID: 18665579

9

Catalytic asymmetric syntheses of tyrosine surrogates.

Han X, Civiello RL, Fang H, Wu D, Gao Q, Chaturvedula PV, Macor JE, Dubowchik GM. Han X, et al. Among authors: dubowchik gm. J Org Chem. 2008 Nov 7;73(21):8502-10. doi: 10.1021/jo801577t. Epub 2008 Oct 15. J Org Chem. 2008. PMID: 18855485

10

Catalytic asymmetric syntheses of alpha-amino and alpha-hydroxyl acid derivatives.

Han X, Jiang XJ, Civiello RL, Degnan AP, Chaturvedula PV, Macor JE, Dubowchik GM. Han X, et al. Among authors: dubowchik gm. J Org Chem. 2009 May 15;74(10):3993-6. doi: 10.1021/jo900368k. J Org Chem. 2009. PMID: 19378930

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

56 results

Search Page

Filters