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321 results

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Page 1
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing.
Francis JM, Zhang CZ, Maire CL, Jung J, Manzo VE, Adalsteinsson VA, Homer H, Haidar S, Blumenstiel B, Pedamallu CS, Ligon AH, Love JC, Meyerson M, Ligon KL. Francis JM, et al. Among authors: ligon ah, ligon kl. Cancer Discov. 2014 Aug;4(8):956-71. doi: 10.1158/2159-8290.CD-13-0879. Epub 2014 Jun 3. Cancer Discov. 2014. PMID: 24893890 Free PMC article.
Marked genomic differences characterize primary and secondary glioblastoma subtypes and identify two distinct molecular and clinical secondary glioblastoma entities.
Maher EA, Brennan C, Wen PY, Durso L, Ligon KL, Richardson A, Khatry D, Feng B, Sinha R, Louis DN, Quackenbush J, Black PM, Chin L, DePinho RA. Maher EA, et al. Among authors: ligon kl. Cancer Res. 2006 Dec 1;66(23):11502-13. doi: 10.1158/0008-5472.CAN-06-2072. Epub 2006 Nov 17. Cancer Res. 2006. PMID: 17114236
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development.
Wiedemeyer R, Brennan C, Heffernan TP, Xiao Y, Mahoney J, Protopopov A, Zheng H, Bignell G, Furnari F, Cavenee WK, Hahn WC, Ichimura K, Collins VP, Chu GC, Stratton MR, Ligon KL, Futreal PA, Chin L. Wiedemeyer R, et al. Among authors: ligon kl. Cancer Cell. 2008 Apr;13(4):355-64. doi: 10.1016/j.ccr.2008.02.010. Cancer Cell. 2008. PMID: 18394558 Free PMC article.
Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.
Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. Schüller U, et al. Among authors: ligon ah, ligon kl. Cancer Cell. 2008 Aug 12;14(2):123-34. doi: 10.1016/j.ccr.2008.07.005. Cancer Cell. 2008. PMID: 18691547 Free PMC article.
Profiling critical cancer gene mutations in clinical tumor samples.
MacConaill LE, Campbell CD, Kehoe SM, Bass AJ, Hatton C, Niu L, Davis M, Yao K, Hanna M, Mondal C, Luongo L, Emery CM, Baker AC, Philips J, Goff DJ, Fiorentino M, Rubin MA, Polyak K, Chan J, Wang Y, Fletcher JA, Santagata S, Corso G, Roviello F, Shivdasani R, Kieran MW, Ligon KL, Stiles CD, Hahn WC, Meyerson ML, Garraway LA. MacConaill LE, et al. Among authors: ligon kl. PLoS One. 2009 Nov 18;4(11):e7887. doi: 10.1371/journal.pone.0007887. PLoS One. 2009. PMID: 19924296 Free PMC article.
CRX is a diagnostic marker of retinal and pineal lineage tumors.
Santagata S, Maire CL, Idbaih A, Geffers L, Correll M, Holton K, Quackenbush J, Ligon KL. Santagata S, et al. Among authors: ligon kl. PLoS One. 2009 Nov 20;4(11):e7932. doi: 10.1371/journal.pone.0007932. PLoS One. 2009. PMID: 19936203 Free PMC article.
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, Kool M, Ligon K, Meyerson M, Mesirov JP, Pomeroy SL. Cho YJ, et al. J Clin Oncol. 2011 Apr 10;29(11):1424-30. doi: 10.1200/JCO.2010.28.5148. Epub 2010 Nov 22. J Clin Oncol. 2011. PMID: 21098324 Free PMC article.
321 results