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The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells.
Wang H, Geng J, Wen X, Bi E, Kossenkov AV, Wolf AI, Tas J, Choi YS, Takata H, Day TJ, Chang LY, Sprout SL, Becker EK, Willen J, Tian L, Wang X, Xiao C, Jiang P, Crotty S, Victora GD, Showe LC, Tucker HO, Erikson J, Hu H. Wang H, et al. Among authors: wang x. Nat Immunol. 2014 Jul;15(7):667-75. doi: 10.1038/ni.2890. Epub 2014 May 25. Nat Immunol. 2014. PMID: 24859450 Free PMC article.
Extracellular matrix protein 1 promotes follicular helper T cell differentiation and antibody production.
He L, Gu W, Wang M, Chang X, Sun X, Zhang Y, Lin X, Yan C, Fan W, Su P, Wang Y, Yi C, Lin G, Li L, Jiang Y, Lu J, Dong C, Wang H, Sun B. He L, et al. Among authors: wang h, wang y, wang m. Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):8621-8626. doi: 10.1073/pnas.1801196115. Epub 2018 Aug 7. Proc Natl Acad Sci U S A. 2018. PMID: 30087185 Free PMC article.
USP21 prevents the generation of T-helper-1-like Treg cells.
Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, Liang R, Zhang Y, Leng Q, Wei G, Shi G, Zhu R, Li D, Wang H, Zheng SG, Xu H, Tsun A, Li B. Li Y, et al. Among authors: wang h, wang s. Nat Commun. 2016 Nov 18;7:13559. doi: 10.1038/ncomms13559. Nat Commun. 2016. PMID: 27857073 Free PMC article.
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