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PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells.
Pirazzi C, Valenti L, Motta BM, Pingitore P, Hedfalk K, Mancina RM, Burza MA, Indiveri C, Ferro Y, Montalcini T, Maglio C, Dongiovanni P, Fargion S, Rametta R, Pujia A, Andersson L, Ghosal S, Levin M, Wiklund O, Iacovino M, Borén J, Romeo S. Pirazzi C, et al. Among authors: motta bm. Hum Mol Genet. 2014 Aug 1;23(15):4077-85. doi: 10.1093/hmg/ddu121. Epub 2014 Mar 25. Hum Mol Genet. 2014. PMID: 24670599 Free PMC article.
The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice.
Fagman JB, Wilhelmson AS, Motta BM, Pirazzi C, Alexanderson C, De Gendt K, Verhoeven G, Holmäng A, Anesten F, Jansson JO, Levin M, Borén J, Ohlsson C, Krettek A, Romeo S, Tivesten Å. Fagman JB, et al. Among authors: motta bm. FASEB J. 2015 Apr;29(4):1540-50. doi: 10.1096/fj.14-259234. Epub 2014 Dec 30. FASEB J. 2015. PMID: 25550469 Free PMC article.
DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection.
Burza MA, Motta BM, Mancina RM, Pingitore P, Pirazzi C, Lepore SM, Spagnuolo R, Doldo P, Russo C, Lazzaro V, Fischer J, Berg T, Aghemo A, Cheroni C, De Francesco R, Fargion S, Colombo M, Datz C, Stickel F, Valenti L, Romeo S. Burza MA, et al. Among authors: motta bm. Hepatology. 2016 Feb;63(2):418-27. doi: 10.1002/hep.28322. Epub 2015 Dec 18. Hepatology. 2016. PMID: 26517016 Free PMC article.
The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.
Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, Borén J, Montalcini T, Pujia A, Wiklund O, Hindy G, Spagnuolo R, Motta BM, Pipitone RM, Craxì A, Fargion S, Nobili V, Käkelä P, Kärjä V, Männistö V, Pihlajamäki J, Reilly DF, Castro-Perez J, Kozlitina J, Valenti L, Romeo S. Mancina RM, et al. Among authors: motta bm. Gastroenterology. 2016 May;150(5):1219-1230.e6. doi: 10.1053/j.gastro.2016.01.032. Epub 2016 Feb 2. Gastroenterology. 2016. PMID: 26850495 Free PMC article.
PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis.
Pingitore P, Dongiovanni P, Motta BM, Meroni M, Lepore SM, Mancina RM, Pelusi S, Russo C, Caddeo A, Rossi G, Montalcini T, Pujia A, Wiklund O, Valenti L, Romeo S. Pingitore P, et al. Among authors: motta bm. Hum Mol Genet. 2016 Dec 1;25(23):5212-5222. doi: 10.1093/hmg/ddw341. Hum Mol Genet. 2016. PMID: 27742777 Free PMC article.
The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage.
Donati B, Motta BM, Pingitore P, Meroni M, Pietrelli A, Alisi A, Petta S, Xing C, Dongiovanni P, del Menico B, Rametta R, Mancina RM, Badiali S, Fracanzani AL, Craxì A, Fargion S, Nobili V, Romeo S, Valenti L. Donati B, et al. Among authors: motta bm. Hepatology. 2016 Mar;63(3):787-98. doi: 10.1002/hep.28370. Epub 2016 Jan 14. Hepatology. 2016. PMID: 26605757
Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease.
Dongiovanni P, Petta S, Maglio C, Fracanzani AL, Pipitone R, Mozzi E, Motta BM, Kaminska D, Rametta R, Grimaudo S, Pelusi S, Montalcini T, Alisi A, Maggioni M, Kärjä V, Borén J, Käkelä P, Di Marco V, Xing C, Nobili V, Dallapiccola B, Craxi A, Pihlajamäki J, Fargion S, Sjöström L, Carlsson LM, Romeo S, Valenti L. Dongiovanni P, et al. Among authors: motta bm. Hepatology. 2015 Feb;61(2):506-14. doi: 10.1002/hep.27490. Hepatology. 2015. PMID: 25251399
37 results