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Page 1
Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids.
Cicerchi C, Li N, Kratzer J, Garcia G, Roncal-Jimenez CA, Tanabe K, Hunter B, Rivard CJ, Sautin YY, Gaucher EA, Johnson RJ, Lanaspa MA. Cicerchi C, et al. Among authors: sautin yy. FASEB J. 2014 Aug;28(8):3339-50. doi: 10.1096/fj.13-243634. Epub 2014 Apr 22. FASEB J. 2014. PMID: 24755741 Free PMC article.
Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and -independent fatty liver.
Lanaspa MA, Sanchez-Lozada LG, Choi YJ, Cicerchi C, Kanbay M, Roncal-Jimenez CA, Ishimoto T, Li N, Marek G, Duranay M, Schreiner G, Rodriguez-Iturbe B, Nakagawa T, Kang DH, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: sautin yy. J Biol Chem. 2012 Nov 23;287(48):40732-44. doi: 10.1074/jbc.M112.399899. Epub 2012 Oct 3. J Biol Chem. 2012. PMID: 23035112 Free PMC article.
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver.
Lanaspa MA, Sanchez-Lozada LG, Cicerchi C, Li N, Roncal-Jimenez CA, Ishimoto T, Le M, Garcia GE, Thomas JB, Rivard CJ, Andres-Hernando A, Hunter B, Schreiner G, Rodriguez-Iturbe B, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: sautin yy. PLoS One. 2012;7(10):e47948. doi: 10.1371/journal.pone.0047948. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23112875 Free PMC article.
Uric acid and fructose: potential biological mechanisms.
Lanaspa MA, Tapia E, Soto V, Sautin Y, Sánchez-Lozada LG. Lanaspa MA, et al. Semin Nephrol. 2011 Sep;31(5):426-32. doi: 10.1016/j.semnephrol.2011.08.006. Semin Nephrol. 2011. PMID: 22000649 Review.
Uric acid: the oxidant-antioxidant paradox.
Sautin YY, Johnson RJ. Sautin YY, et al. Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):608-19. doi: 10.1080/15257770802138558. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18600514 Free PMC article.
Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake.
Roncal-Jimenez CA, Lanaspa MA, Rivard CJ, Nakagawa T, Sanchez-Lozada LG, Jalal D, Andres-Hernando A, Tanabe K, Madero M, Li N, Cicerchi C, Mc Fann K, Sautin YY, Johnson RJ. Roncal-Jimenez CA, et al. Among authors: sautin yy. Metabolism. 2011 Sep;60(9):1259-70. doi: 10.1016/j.metabol.2011.01.008. Epub 2011 Apr 12. Metabolism. 2011. PMID: 21489572 Free PMC article.
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sánchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ. Ishimoto T, et al. Among authors: sautin yy. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4320-5. doi: 10.1073/pnas.1119908109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371574 Free PMC article.
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.
Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. Ishimoto T, et al. Among authors: sautin yy. Hepatology. 2013 Nov;58(5):1632-43. doi: 10.1002/hep.26594. Epub 2013 Oct 8. Hepatology. 2013. PMID: 23813872 Free PMC article.
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.
Lanaspa MA, Ishimoto T, Li N, Cicerchi C, Orlicky DJ, Ruzycki P, Rivard C, Inaba S, Roncal-Jimenez CA, Bales ES, Diggle CP, Asipu A, Petrash JM, Kosugi T, Maruyama S, Sanchez-Lozada LG, McManaman JL, Bonthron DT, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: sautin yy. Nat Commun. 2013;4:2434. doi: 10.1038/ncomms3434. Nat Commun. 2013. PMID: 24022321 Free PMC article.
45 results