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Peripherally selective diphenyl purine antagonist of the CB1 receptor.
Fulp A, Bortoff K, Zhang Y, Snyder R, Fennell T, Marusich JA, Wiley JL, Seltzman H, Maitra R. Fulp A, et al. Among authors: snyder r. J Med Chem. 2013 Oct 24;56(20):8066-72. doi: 10.1021/jm401129n. Epub 2013 Sep 27. J Med Chem. 2013. PMID: 24041123 Free PMC article.
Distribution and biomarkers of carbon-14-labeled fullerene C60 ([(14) C(U)]C60 ) in female rats and mice for up to 30 days after intravenous exposure.
Sumner SC, Snyder RW, Wingard C, Mortensen NP, Holland NA, Shannahan JH, Dhungana S, Pathmasiri W, Han L, Lewin AH, Fennell TR. Sumner SC, et al. Among authors: snyder rw. J Appl Toxicol. 2015 Dec;35(12):1452-64. doi: 10.1002/jat.3110. Epub 2015 Feb 27. J Appl Toxicol. 2015. PMID: 25727383 Free PMC article.
Pyrazole antagonists of the CB1 receptor with reduced brain penetration.
Fulp A, Zhang Y, Bortoff K, Seltzman H, Snyder R, Wiethe R, Amato G, Maitra R. Fulp A, et al. Among authors: snyder r. Bioorg Med Chem. 2016 Mar 1;24(5):1063-70. doi: 10.1016/j.bmc.2016.01.033. Epub 2016 Jan 18. Bioorg Med Chem. 2016. PMID: 26827137 Free PMC article.
Potent and Selective Tetrahydroisoquinoline Kappa Opioid Receptor Antagonists of Lead Compound (3 R)- N-[1 R)-1-(Cyclohexylmethyl)-2-methylpropyl]-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide (CDTic).
Kormos CM, Ondachi PW, Runyon SP, Thomas JB, Mascarella SW, Decker AM, Navarro HA, Fennell TR, Snyder RW, Carroll FI. Kormos CM, et al. Among authors: snyder rw. J Med Chem. 2018 Sep 13;61(17):7546-7559. doi: 10.1021/acs.jmedchem.8b00674. Epub 2018 Aug 29. J Med Chem. 2018. PMID: 30032602 Free PMC article.
1,642 results