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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. Seguin L, et al. Among authors: weis sm. Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20. Nat Cell Biol. 2014. PMID: 24747441 Free PMC article.
Robo4 counteracts VEGF signaling.
Acevedo LM, Weis SM, Cheresh DA. Acevedo LM, et al. Among authors: weis sm. Nat Med. 2008 Apr;14(4):372-3. doi: 10.1038/nm0408-372. Nat Med. 2008. PMID: 18391935 No abstract available.
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