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The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells.
Bosch A, Panoutsopoulou K, Corominas JM, Gimeno R, Moreno-Bueno G, Martín-Caballero J, Morales S, Lobato T, Martínez-Romero C, Farias EF, Mayol X, Cano A, Hernández-Muñoz I. Bosch A, et al. Oncotarget. 2014 Apr 30;5(8):2065-76. doi: 10.18632/oncotarget.1779. Oncotarget. 2014. PMID: 24742605 Free PMC article.
Modeling SARS-CoV-2: Comparative Pathology in Rhesus Macaque and Golden Syrian Hamster Models.
Choudhary S, Kanevsky I, Yildiz S, Sellers RS, Swanson KA, Franks T, Rathnasinghe R, Munoz-Moreno R, Jangra S, Gonzalez O, Meade P, Coskran T, Qian J, Lanz TA, Johnson JG, Tierney CA, Smith JD, Tompkins K, Illenberger A, Corts P, Ciolino T, Dormitzer PR, Dick EJ Jr, Shivanna V, Hall-Ursone S, Cole J, Kaushal D, Fontenot JA, Martinez-Romero C, McMahon M, Krammer F, Schotsaert M, García-Sastre A. Choudhary S, et al. Among authors: martinez romero c. Toxicol Pathol. 2022 Apr;50(3):280-293. doi: 10.1177/01926233211072767. Epub 2022 Feb 5. Toxicol Pathol. 2022. PMID: 35128980 Free PMC article.
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A.
White KM, Rosales R, Yildiz S, Kehrer T, Miorin L, Moreno E, Jangra S, Uccellini MB, Rathnasinghe R, Coughlan L, Martinez-Romero C, Batra J, Rojc A, Bouhaddou M, Fabius JM, Obernier K, Dejosez M, Guillén MJ, Losada A, Avilés P, Schotsaert M, Zwaka T, Vignuzzi M, Shokat KM, Krogan NJ, García-Sastre A. White KM, et al. Among authors: martinez romero c. Science. 2021 Feb 26;371(6532):926-931. doi: 10.1126/science.abf4058. Epub 2021 Jan 25. Science. 2021. PMID: 33495306 Free PMC article.
Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera.
Rathnasinghe R, Jangra S, Ye C, Cupic A, Singh G, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Yeung ST, Mena I, Gillespie V, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Corley MJ, Richt JA, De Geest BG, Miorin L; PVI study group; Krammer F, Martinez-Sobrido L, Simon V, García-Sastre A, Schotsaert M. Rathnasinghe R, et al. Among authors: martinez romero c. Nat Commun. 2022 Jul 7;13(1):3921. doi: 10.1038/s41467-022-30763-0. Nat Commun. 2022. PMID: 35798721 Free PMC article.
Against the clock towards new Ebola virus therapies.
Martínez-Romero C, García-Sastre A. Martínez-Romero C, et al. Virus Res. 2015 Nov 2;209:4-10. doi: 10.1016/j.virusres.2015.05.025. Epub 2015 Jun 6. Virus Res. 2015. PMID: 26057711 Review.
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera.
Rathnasinghe R, Jangra S, Cupic A, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Mena I, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Richt JA, De Geest BG, Miorin L; PVI study group; Krammer F, Simon V, García-Sastre A, Schotsaert M. Rathnasinghe R, et al. Among authors: martinez romero c. medRxiv [Preprint]. 2021 Jan 20:2021.01.19.21249592. doi: 10.1101/2021.01.19.21249592. medRxiv. 2021. PMID: 33501468 Free PMC article. Preprint.
Virus-induced senescence is a driver and therapeutic target in COVID-19.
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter-Pechanska P, Wyler E, Belenki D, Kaltenbrunner S, Pammer M, Kausche L, Firsching TC, Dietert K, Schotsaert M, Martínez-Romero C, Singh G, Kunz S, Niemeyer D, Ghanem R, Salzer HJF, Paar C, Mülleder M, Uccellini M, Michaelis EG, Khan A, Lau A, Schönlein M, Habringer A, Tomasits J, Adler JM, Kimeswenger S, Gruber AD, Hoetzenecker W, Steinkellner H, Purfürst B, Motz R, Di Pierro F, Lamprecht B, Osterrieder N, Landthaler M, Drosten C, García-Sastre A, Langer R, Ralser M, Eils R, Reimann M, Fan DNY, Schmitt CA. Lee S, et al. Among authors: martinez romero c. Nature. 2021 Nov;599(7884):283-289. doi: 10.1038/s41586-021-03995-1. Epub 2021 Sep 13. Nature. 2021. PMID: 34517409
Antiviral Role of IFITM Proteins in African Swine Fever Virus Infection.
Muñoz-Moreno R, Cuesta-Geijo MÁ, Martínez-Romero C, Barrado-Gil L, Galindo I, García-Sastre A, Alonso C. Muñoz-Moreno R, et al. PLoS One. 2016 Apr 26;11(4):e0154366. doi: 10.1371/journal.pone.0154366. eCollection 2016. PLoS One. 2016. PMID: 27116236 Free PMC article.
31 results