Baughman TM - Search Results

1

Design and synthesis of spirocyclic compounds as HCV replication inhibitors by targeting viral NS4B protein.

Tai VW, Garrido D, Price DJ, Maynard A, Pouliot JJ, Xiong Z, Seal JW 3rd, Creech KL, Kryn LH, Baughman TM, Peat AJ. Tai VW, et al. Among authors: baughman tm. Bioorg Med Chem Lett. 2014 May 15;24(10):2288-94. doi: 10.1016/j.bmcl.2014.03.080. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24731273

2

Synthesis and pharmacokinetic profile of highly deuterated brecanavir analogs.

Velthuisen EJ, Baughman TM, Johns BA, Temelkoff DP, Weatherhead JG. Velthuisen EJ, et al. Among authors: baughman tm. Eur J Med Chem. 2013 May;63:202-12. doi: 10.1016/j.ejmech.2013.02.001. Epub 2013 Feb 14. Eur J Med Chem. 2013. PMID: 23474906

3

Evaluation of the metabolism of propranolol by linear ion trap technology in mouse, rat, dog, monkey, and human cryopreserved hepatocytes.

Baughman TM, Talarico CL, Soglia JR. Baughman TM, et al. Rapid Commun Mass Spectrom. 2009 Jul;23(14):2146-50. doi: 10.1002/rcm.4130. Rapid Commun Mass Spectrom. 2009. PMID: 19517456

4

Metabolic activation of pioglitazone identified from rat and human liver microsomes and freshly isolated hepatocytes.

Baughman TM, Graham RA, Wells-Knecht K, Silver IS, Tyler LO, Wells-Knecht M, Zhao Z. Baughman TM, et al. Drug Metab Dispos. 2005 Jun;33(6):733-8. doi: 10.1124/dmd.104.002683. Epub 2005 Mar 11. Drug Metab Dispos. 2005. PMID: 15764718

5

Determination of zanamivir in rat and monkey plasma by positive ion hydrophilic interaction chromatography (HILIC)/tandem mass spectrometry.

Baughman TM, Wright WL, Hutton KA. Baughman TM, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 1;852(1-2):505-11. doi: 10.1016/j.jchromb.2007.02.006. Epub 2007 Feb 15. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17324643

6

P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine.

Polli JW, Baughman TM, Humphreys JE, Jordan KH, Mote AL, Salisbury JA, Tippin TK, Serabjit-Singh CJ. Polli JW, et al. Among authors: baughman tm. J Pharm Sci. 2003 Oct;92(10):2082-9. doi: 10.1002/jps.10453. J Pharm Sci. 2003. PMID: 14502547

7

The systemic exposure of an N-methyl-D-aspartate receptor antagonist is limited in mice by the P-glycoprotein and breast cancer resistance protein efflux transporters.

Polli JW, Baughman TM, Humphreys JE, Jordan KH, Mote AL, Webster LO, Barnaby RJ, Vitulli G, Bertolotti L, Read KD, Serabjit-Singh CJ. Polli JW, et al. Among authors: baughman tm. Drug Metab Dispos. 2004 Jul;32(7):722-6. doi: 10.1124/dmd.32.7.722. Drug Metab Dispos. 2004. PMID: 15205387

8

Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations.

Ehlhardt WJ, Woodland JM, Baughman TM, Vandenbranden M, Wrighton SA, Kroin JS, Norman BH, Maple SR. Ehlhardt WJ, et al. Among authors: baughman tm. Drug Metab Dispos. 1998 Jan;26(1):42-51. Drug Metab Dispos. 1998. PMID: 9443851

9

Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein.

Starling JJ, Shepard RL, Cao J, Law KL, Norman BH, Kroin JS, Ehlhardt WJ, Baughman TM, Winter MA, Bell MG, Shih C, Gruber J, Elmquist WF, Dantzig AH. Starling JJ, et al. Among authors: baughman tm. Adv Enzyme Regul. 1997;37:335-47. doi: 10.1016/s0065-2571(96)00021-0. Adv Enzyme Regul. 1997. PMID: 9381979

10

Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979.

Dantzig AH, Shepard RL, Cao J, Law KL, Ehlhardt WJ, Baughman TM, Bumol TF, Starling JJ. Dantzig AH, et al. Among authors: baughman tm. Cancer Res. 1996 Sep 15;56(18):4171-9. Cancer Res. 1996. PMID: 8797588

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