Yates PD - Search Results

1

A "middle-out" approach to human pharmacokinetic predictions for OATP substrates using physiologically-based pharmacokinetic modeling.

Li R, Barton HA, Yates PD, Ghosh A, Wolford AC, Riccardi KA, Maurer TS. Li R, et al. Among authors: yates pd. J Pharmacokinet Pharmacodyn. 2014 Jun;41(3):197-209. doi: 10.1007/s10928-014-9357-1. Epub 2014 Apr 10. J Pharmacokinet Pharmacodyn. 2014. PMID: 24718648

2

Comparison of Species and Cell-Type Differences in Fraction Unbound of Liver Tissues, Hepatocytes, and Cell Lines.

Riccardi K, Ryu S, Lin J, Yates P, Tess D, Li R, Singh D, Holder BR, Kapinos B, Chang G, Di L. Riccardi K, et al. Drug Metab Dispos. 2018 Apr;46(4):415-421. doi: 10.1124/dmd.117.079152. Epub 2018 Feb 2. Drug Metab Dispos. 2018. PMID: 29437874

3

Plasma Protein Binding of Challenging Compounds.

Riccardi K, Cawley S, Yates PD, Chang C, Funk C, Niosi M, Lin J, Di L. Riccardi K, et al. Among authors: yates pd. J Pharm Sci. 2015 Aug;104(8):2627-36. doi: 10.1002/jps.24506. Epub 2015 Jun 2. J Pharm Sci. 2015. PMID: 26037784

4

The impact of low temperature on fraction unbound for plasma and tissue.

Ryu S, Novak JJ, Patel R, Yates P, Di L. Ryu S, et al. Biopharm Drug Dispos. 2018 Nov;39(9):437-442. doi: 10.1002/bdd.2160. Epub 2018 Nov 13. Biopharm Drug Dispos. 2018. PMID: 30362129

5

11β-Hydroxysteroid Dehydrogenase 1 Human Tissue Distribution, Selective Inhibitor, and Role in Doxorubicin Metabolism.

Yang X, Hua W, Ryu S, Yates P, Chang C, Zhang H, Di L. Yang X, et al. Drug Metab Dispos. 2018 Jul;46(7):1023-1029. doi: 10.1124/dmd.118.081083. Epub 2018 Apr 19. Drug Metab Dispos. 2018. PMID: 29674492

6

Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment.

Wong SG, Ramsden D, Dallas S, Fung C, Einolf HJ, Palamanda J, Chen L, Goosen TC, Siu YA, Zhang G, Tweedie D, Hariparsad N, Jones B, Yates PD. Wong SG, et al. Among authors: yates pd. Drug Metab Dispos. 2021 Jan;49(1):94-110. doi: 10.1124/dmd.120.000055. Epub 2020 Nov 2. Drug Metab Dispos. 2021. PMID: 33139460

7

Statistical methods for analysis of time-dependent inhibition of cytochrome p450 enzymes.

Yates P, Eng H, Di L, Obach RS. Yates P, et al. Drug Metab Dispos. 2012 Dec;40(12):2289-96. doi: 10.1124/dmd.112.047233. Epub 2012 Aug 31. Drug Metab Dispos. 2012. PMID: 22942318

8

Feasibility of Singlet Analysis for Ligand Binding Assays: a Retrospective Examination of Data Generated Using the Gyrolab Platform.

Clark TH, Yates PD, Chunyk AG, Joyce AP, Wu A, Pop-Damkov P, Zhang Y, Dreher EA, Tylaska LA, Wentland JA, Pelletier KB, King LE, Ray CA. Clark TH, et al. Among authors: yates pd. AAPS J. 2016 Sep;18(5):1300-1308. doi: 10.1208/s12248-016-9944-8. Epub 2016 Jul 11. AAPS J. 2016. PMID: 27401185

9

An inferential framework for biological network hypothesis tests.

Yates PD, Mukhopadhyay ND. Yates PD, et al. BMC Bioinformatics. 2013 Mar 14;14:94. doi: 10.1186/1471-2105-14-94. BMC Bioinformatics. 2013. PMID: 23496778 Free PMC article.

10

Downstream effects of striatal-enriched protein tyrosine phosphatase reduction on RNA expression in vivo and in vitro.

Reinhart VL, Nguyen T, Gerwien R Jr, Kuhn M, Yates PD, Lanz TA. Reinhart VL, et al. Among authors: yates pd. Neuroscience. 2014 Oct 10;278:62-9. doi: 10.1016/j.neuroscience.2014.08.002. Epub 2014 Aug 15. Neuroscience. 2014. PMID: 25130559

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