Wang D - Search Results

1

Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.

Xu L, Butler KV, Chong J, Wengel J, Kool ET, Wang D. Xu L, et al. Among authors: wang d. Nucleic Acids Res. 2014 May;42(9):5863-70. doi: 10.1093/nar/gku238. Epub 2014 Apr 1. Nucleic Acids Res. 2014. PMID: 24692664 Free PMC article.

2

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis.

Wang D, Bushnell DA, Westover KD, Kaplan CD, Kornberg RD. Wang D, et al. Cell. 2006 Dec 1;127(5):941-54. doi: 10.1016/j.cell.2006.11.023. Cell. 2006. PMID: 17129781 Free PMC article.

3

Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.

Wang D, Bushnell DA, Huang X, Westover KD, Levitt M, Kornberg RD. Wang D, et al. Science. 2009 May 29;324(5931):1203-6. doi: 10.1126/science.1168729. Science. 2009. PMID: 19478184 Free PMC article.

4

X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.

Wang D, Zhu G, Huang X, Lippard SJ. Wang D, et al. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9584-9. doi: 10.1073/pnas.1002565107. Epub 2010 May 6. Proc Natl Acad Sci U S A. 2010. PMID: 20448203 Free PMC article.

5

Dissecting chemical interactions governing RNA polymerase II transcriptional fidelity.

Kellinger MW, Ulrich S, Chong J, Kool ET, Wang D. Kellinger MW, et al. Among authors: wang d. J Am Chem Soc. 2012 May 16;134(19):8231-40. doi: 10.1021/ja302077d. Epub 2012 May 2. J Am Chem Soc. 2012. PMID: 22509745 Free PMC article.

6

5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

Kellinger MW, Song CX, Chong J, Lu XY, He C, Wang D. Kellinger MW, et al. Among authors: wang d. Nat Struct Mol Biol. 2012 Aug;19(8):831-3. doi: 10.1038/nsmb.2346. Epub 2012 Jul 22. Nat Struct Mol Biol. 2012. PMID: 22820989 Free PMC article.

7

Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis.

Kellinger MW, Park GY, Chong J, Lippard SJ, Wang D. Kellinger MW, et al. Among authors: wang d. J Am Chem Soc. 2013 Sep 4;135(35):13054-61. doi: 10.1021/ja405475y. Epub 2013 Aug 25. J Am Chem Soc. 2013. PMID: 23927577 Free PMC article.

8

A chemical perspective on transcriptional fidelity: dominant contributions of sugar integrity revealed by unlocked nucleic acids.

Xu L, Plouffe SW, Chong J, Wengel J, Wang D. Xu L, et al. Among authors: wang d. Angew Chem Int Ed Engl. 2013 Nov 18;52(47):12341-5. doi: 10.1002/anie.201307661. Epub 2013 Oct 24. Angew Chem Int Ed Engl. 2013. PMID: 24167045 Free PMC article.

9

Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.

Xu L, Da L, Plouffe SW, Chong J, Kool E, Wang D. Xu L, et al. Among authors: wang d. DNA Repair (Amst). 2014 Jul;19:71-83. doi: 10.1016/j.dnarep.2014.03.024. Epub 2014 Apr 21. DNA Repair (Amst). 2014. PMID: 24767259 Free PMC article. Review.

10

A Chemical Probe Targets DNA 5-Formylcytosine Sites and Inhibits TDG Excision, Polymerases Bypass, and Gene Expression.

Xu L, Chen YC, Nakajima S, Chong J, Wang L, Lan L, Zhang C, Wang D. Xu L, et al. Among authors: wang l, wang d. Chem Sci. 2014 Feb 1;5(2):567-574. doi: 10.1039/C3SC51849C. Chem Sci. 2014. PMID: 24883182 Free PMC article.

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