Davies FE - Search Results

1

Preclinical evaluation of imaging biomarkers for prostate cancer bone metastasis and response to cabozantinib.

Graham TJ, Box G, Tunariu N, Crespo M, Spinks TJ, Miranda S, Attard G, de Bono J, Eccles SA, Davies FE, Robinson SP. Graham TJ, et al. Among authors: davies fe. J Natl Cancer Inst. 2014 Apr;106(4):dju033. doi: 10.1093/jnci/dju033. Epub 2014 Mar 14. J Natl Cancer Inst. 2014. PMID: 24634505

2

Characterization of a novel mouse model of multiple myeloma and its use in preclinical therapeutic assessment.

Fryer RA, Graham TJ, Smith EM, Walker-Samuel S, Morgan GJ, Robinson SP, Davies FE. Fryer RA, et al. Among authors: davies fe. PLoS One. 2013;8(2):e57641. doi: 10.1371/journal.pone.0057641. Epub 2013 Feb 21. PLoS One. 2013. PMID: 23437401 Free PMC article.

3

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

Fok JHL, Hedayat S, Zhang L, Aronson LI, Mirabella F, Pawlyn C, Bright MD, Wardell CP, Keats JJ, De Billy E, Rye CS, Chessum NEA, Jones K, Morgan GJ, Eccles SA, Workman P, Davies FE. Fok JHL, et al. Among authors: davies fe. Clin Cancer Res. 2018 May 15;24(10):2395-2407. doi: 10.1158/1078-0432.CCR-17-1594. Epub 2018 Feb 1. Clin Cancer Res. 2018. PMID: 29391353 Free PMC article.

4

Assessing response of myeloma bone disease with diffusion-weighted MRI.

Messiou C, Giles S, Collins DJ, West S, Davies FE, Morgan GJ, Desouza NM. Messiou C, et al. Among authors: davies fe. Br J Radiol. 2012 Dec;85(1020):e1198-203. doi: 10.1259/bjr/52759767. Br J Radiol. 2012. PMID: 23175485 Free PMC article.

5

Whole-body diffusion-weighted MR imaging for assessment of treatment response in myeloma.

Giles SL, Messiou C, Collins DJ, Morgan VA, Simpkin CJ, West S, Davies FE, Morgan GJ, deSouza NM. Giles SL, et al. Among authors: davies fe. Radiology. 2014 Jun;271(3):785-94. doi: 10.1148/radiol.13131529. Epub 2014 Jan 21. Radiology. 2014. PMID: 24475858

6

Assessing myeloma bone disease with whole-body diffusion-weighted imaging: comparison with x-ray skeletal survey by region and relationship with laboratory estimates of disease burden.

Giles SL, deSouza NM, Collins DJ, Morgan VA, West S, Davies FE, Morgan GJ, Messiou C. Giles SL, et al. Among authors: davies fe. Clin Radiol. 2015 Jun;70(6):614-21. doi: 10.1016/j.crad.2015.02.013. Epub 2015 Mar 19. Clin Radiol. 2015. PMID: 25799364 Free PMC article.

7

Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease.

Colombano G, Caldwell JJ, Matthews TP, Bhatia C, Joshi A, McHardy T, Mok NY, Newbatt Y, Pickard L, Strover J, Hedayat S, Walton MI, Myers SM, Jones AM, Saville H, McAndrew C, Burke R, Eccles SA, Davies FE, Bayliss R, Collins I. Colombano G, et al. Among authors: davies fe. J Med Chem. 2019 Mar 14;62(5):2447-2465. doi: 10.1021/acs.jmedchem.8b01721. Epub 2019 Mar 5. J Med Chem. 2019. PMID: 30779566 Free PMC article.

8

Whole-body diffusion-weighted MRI: a new gold standard for assessing disease burden in patients with multiple myeloma?

Pawlyn C, Fowkes L, Otero S, Jones JR, Boyd KD, Davies FE, Morgan GJ, Collins DJ, Sharma B, Riddell A, Kaiser MF, Messiou C. Pawlyn C, et al. Among authors: davies fe. Leukemia. 2016 Jun;30(6):1446-8. doi: 10.1038/leu.2015.338. Epub 2015 Dec 9. Leukemia. 2016. PMID: 26648535 Free PMC article. No abstract available.

9

Identification of autophosphorylation inhibitors of the inositol-requiring enzyme 1 alpha (IRE1α) by high-throughput screening using a DELFIA assay.

Newbatt Y, Hardcastle A, McAndrew PC, Strover JA, Mirza A, Morgan GJ, Burke R, Davies FE, Collins I, van Montfort RL. Newbatt Y, et al. Among authors: davies fe. J Biomol Screen. 2013 Mar;18(3):298-308. doi: 10.1177/1087057112465647. Epub 2012 Nov 8. J Biomol Screen. 2013. PMID: 23139381

10

The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway.

Smith EM, Zhang L, Walker BA, Davenport EL, Aronson LI, Krige D, Hooftman L, Drummond AH, Morgan GJ, Davies FE. Smith EM, et al. Among authors: davies fe. Oncotarget. 2015 Jul 10;6(19):17314-27. doi: 10.18632/oncotarget.1168. Oncotarget. 2015. PMID: 26015393 Free PMC article.

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