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Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.
Lee EC, Liang Q, Ali H, Bayliss L, Beasley A, Bloomfield-Gerdes T, Bonoli L, Brown R, Campbell J, Carpenter A, Chalk S, Davis A, England N, Fane-Dremucheva A, Franz B, Germaschewski V, Holmes H, Holmes S, Kirby I, Kosmac M, Legent A, Lui H, Manin A, O'Leary S, Paterson J, Sciarrillo R, Speak A, Spensberger D, Tuffery L, Waddell N, Wang W, Wells S, Wong V, Wood A, Owen MJ, Friedrich GA, Bradley A. Lee EC, et al. Among authors: liang q. Nat Biotechnol. 2014 Apr;32(4):356-63. doi: 10.1038/nbt.2825. Epub 2014 Mar 16. Nat Biotechnol. 2014. PMID: 24633243
Agouti C57BL/6N embryonic stem cells for mouse genetic resources.
Pettitt SJ, Liang Q, Rairdan XY, Moran JL, Prosser HM, Beier DR, Lloyd KC, Bradley A, Skarnes WC. Pettitt SJ, et al. Among authors: liang q. Nat Methods. 2009 Jul;6(7):493-5. doi: 10.1038/nmeth.1342. Epub 2009 Jun 14. Nat Methods. 2009. PMID: 19525957 Free PMC article.
An Antibody Targeting ICOS Increases Intratumoral Cytotoxic to Regulatory T-cell Ratio and Induces Tumor Regression.
Sainson RCA, Thotakura AK, Kosmac M, Borhis G, Parveen N, Kimber R, Carvalho J, Henderson SJ, Pryke KL, Okell T, O'Leary S, Ball S, Van Krinks C, Gamand L, Taggart E, Pring EJ, Ali H, Craig H, Wong VWY, Liang Q, Rowlands RJ, Lecointre M, Campbell J, Kirby I, Melvin D, Germaschewski V, Oelmann E, Quaratino S, McCourt M. Sainson RCA, et al. Among authors: liang q. Cancer Immunol Res. 2020 Dec;8(12):1568-1582. doi: 10.1158/2326-6066.CIR-20-0034. Epub 2020 Sep 30. Cancer Immunol Res. 2020. PMID: 32999002
Extensive genomic copy number variation in embryonic stem cells.
Liang Q, Conte N, Skarnes WC, Bradley A. Liang Q, et al. Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17453-6. doi: 10.1073/pnas.0805638105. Epub 2008 Nov 6. Proc Natl Acad Sci U S A. 2008. PMID: 18988746 Free PMC article.
Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Scally SW, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, Reponen S, Nguyen N, Giladi E, Rämisch S, Yusibov V, Bradley A, Lemiale F, Schief WR, Emerling D, Kellam P, King CR, Julien JP. Scally SW, et al. Among authors: liang q. Nat Commun. 2017 Nov 16;8(1):1568. doi: 10.1038/s41467-017-01924-3. Nat Commun. 2017. PMID: 29146922 Free PMC article.
Mobilization of giant piggyBac transposons in the mouse genome.
Li MA, Turner DJ, Ning Z, Yusa K, Liang Q, Eckert S, Rad L, Fitzgerald TW, Craig NL, Bradley A. Li MA, et al. Among authors: liang q. Nucleic Acids Res. 2011 Dec;39(22):e148. doi: 10.1093/nar/gkr764. Epub 2011 Sep 24. Nucleic Acids Res. 2011. PMID: 21948799 Free PMC article.
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter Š, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, Kellam P, Zavala F, Ward AB, Wilson IA. Oyen D, et al. Among authors: liang q. PLoS Pathog. 2020 Mar 9;16(3):e1008373. doi: 10.1371/journal.ppat.1008373. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32150583 Free PMC article.
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes.
de la Rosa J, Weber J, Friedrich MJ, Li Y, Rad L, Ponstingl H, Liang Q, de Quirós SB, Noorani I, Metzakopian E, Strong A, Li MA, Astudillo A, Fernández-García MT, Fernández-García MS, Hoffman GJ, Fuente R, Vassiliou GS, Rad R, López-Otín C, Bradley A, Cadiñanos J. de la Rosa J, et al. Among authors: liang q. Nat Genet. 2017 May;49(5):730-741. doi: 10.1038/ng.3817. Epub 2017 Mar 20. Nat Genet. 2017. PMID: 28319090 Free PMC article.
4,606 results