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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.
Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patané G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P. Lupi R, et al. Among authors: dotta f. Diabetes. 2002 May;51(5):1437-42. doi: 10.2337/diabetes.51.5.1437. Diabetes. 2002. PMID: 11978640
Innate immunity and the pathogenesis of type 1 diabetes.
Grieco FA, Vendrame F, Spagnuolo I, Dotta F. Grieco FA, et al. Among authors: dotta f. Semin Immunopathol. 2011 Jan;33(1):57-66. doi: 10.1007/s00281-010-0206-z. Epub 2010 Apr 10. Semin Immunopathol. 2011. PMID: 20383637 Review.
Virus infections: lessons from pancreas histology.
Dotta F, Galleri L, Sebastiani G, Vendrame F. Dotta F, et al. Curr Diab Rep. 2010 Oct;10(5):357-61. doi: 10.1007/s11892-010-0137-z. Curr Diab Rep. 2010. PMID: 20665131 Review.
Efficacy and safety of exenatide once weekly versus metformin, pioglitazone, and sitagliptin used as monotherapy in drug-naive patients with type 2 diabetes (DURATION-4): a 26-week double-blind study.
Russell-Jones D, Cuddihy RM, Hanefeld M, Kumar A, González JG, Chan M, Wolka AM, Boardman MK; DURATION-4 Study Group. Russell-Jones D, et al. Diabetes Care. 2012 Feb;35(2):252-8. doi: 10.2337/dc11-1107. Epub 2011 Dec 30. Diabetes Care. 2012. PMID: 22210563 Free PMC article. Clinical Trial.
289 results