Caldwell JT - Search Results

1

Acute myeloid leukemia cells harboring MLL fusion genes or with the acute promyelocytic leukemia phenotype are sensitive to the Bcl-2-selective inhibitor ABT-199.

Niu X, Wang G, Wang Y, Caldwell JT, Edwards H, Xie C, Taub JW, Li C, Lin H, Ge Y. Niu X, et al. Among authors: caldwell jt. Leukemia. 2014 Jul;28(7):1557-60. doi: 10.1038/leu.2014.72. Epub 2014 Feb 17. Leukemia. 2014. PMID: 24531733 Free PMC article. No abstract available.

2

CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells.

Qi W, Xie C, Li C, Caldwell JT, Edwards H, Taub JW, Wang Y, Lin H, Ge Y. Qi W, et al. Among authors: caldwell jt. J Hematol Oncol. 2014 Aug 1;7:53. doi: 10.1186/s13045-014-0053-9. J Hematol Oncol. 2014. PMID: 25084614 Free PMC article.

3

Prognosis and management of acute myeloid leukemia in patients with Down syndrome.

Caldwell JT, Ge Y, Taub JW. Caldwell JT, et al. Expert Rev Hematol. 2014 Dec;7(6):831-40. doi: 10.1586/17474086.2014.959923. Epub 2014 Sep 18. Expert Rev Hematol. 2014. PMID: 25231553 Free PMC article. Review.

4

Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.

Xie C, Edwards H, Caldwell JT, Wang G, Taub JW, Ge Y. Xie C, et al. Among authors: caldwell jt. Mol Oncol. 2015 Feb;9(2):409-21. doi: 10.1016/j.molonc.2014.09.008. Epub 2014 Oct 2. Mol Oncol. 2015. PMID: 25308513 Free PMC article.

5

Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.

Niu X, Zhao J, Ma J, Xie C, Edwards H, Wang G, Caldwell JT, Xiang S, Zhang X, Chu R, Wang ZJ, Lin H, Taub JW, Ge Y. Niu X, et al. Among authors: caldwell jt. Clin Cancer Res. 2016 Sep 1;22(17):4440-51. doi: 10.1158/1078-0432.CCR-15-3057. Epub 2016 Apr 21. Clin Cancer Res. 2016. PMID: 27103402 Free PMC article.

6

Panobinostat synergistically enhances the cytotoxic effects of cisplatin, doxorubicin or etoposide on high-risk neuroblastoma cells.

Wang G, Edwards H, Caldwell JT, Buck SA, Qing WY, Taub JW, Ge Y, Wang Z. Wang G, et al. Among authors: caldwell jt. PLoS One. 2013 Sep 30;8(9):e76662. doi: 10.1371/journal.pone.0076662. eCollection 2013. PLoS One. 2013. PMID: 24098799 Free PMC article.

7

Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51.

Xie C, Drenberg C, Edwards H, Caldwell JT, Chen W, Inaba H, Xu X, Buck SA, Taub JW, Baker SD, Ge Y. Xie C, et al. Among authors: caldwell jt. PLoS One. 2013 Nov 11;8(11):e79106. doi: 10.1371/journal.pone.0079106. eCollection 2013. PLoS One. 2013. PMID: 24244429 Free PMC article. Clinical Trial.

8

Targeting the wee1 kinase for treatment of pediatric Down syndrome acute myeloid leukemia.

Caldwell JT, Edwards H, Buck SA, Ge Y, Taub JW. Caldwell JT, et al. Pediatr Blood Cancer. 2014 Oct;61(10):1767-73. doi: 10.1002/pbc.25081. Epub 2014 Jun 24. Pediatr Blood Cancer. 2014. PMID: 24962331 Free PMC article.

9

Synergistic antitumor interactions between MK-1775 and panobinostat in preclinical models of pancreatic cancer.

Wang G, Niu X, Zhang W, Caldwell JT, Edwards H, Chen W, Taub JW, Zhao L, Ge Y. Wang G, et al. Among authors: caldwell jt. Cancer Lett. 2015 Jan 28;356(2 Pt B):656-68. doi: 10.1016/j.canlet.2014.10.015. Epub 2014 Oct 18. Cancer Lett. 2015. PMID: 25458954 Free PMC article.

10

Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.

Caldwell JT, Edwards H, Dombkowski AA, Buck SA, Matherly LH, Ge Y, Taub JW. Caldwell JT, et al. PLoS One. 2013 Jul 10;8(7):e68601. doi: 10.1371/journal.pone.0068601. Print 2013. PLoS One. 2013. PMID: 23874683 Free PMC article.

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