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Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles.
List EO, Berryman DE, Funk K, Jara A, Kelder B, Wang F, Stout MB, Zhi X, Sun L, White TA, LeBrasseur NK, Pirtskhalava T, Tchkonia T, Jensen EA, Zhang W, Masternak MM, Kirkland JL, Miller RA, Bartke A, Kopchick JJ. List EO, et al. Among authors: wang f. Endocrinology. 2014 May;155(5):1793-805. doi: 10.1210/en.2013-2086. Epub 2014 Feb 11. Endocrinology. 2014. PMID: 24517230 Free PMC article.
Is altered expression of hepatic insulin-related genes in growth hormone receptor knockout mice due to GH resistance or a difference in biological life spans?
Panici JA, Wang F, Bonkowski MS, Spong A, Bartke A, Pawlikowska L, Kwok PY, Masternak MM. Panici JA, et al. Among authors: wang f. J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1126-33. doi: 10.1093/gerona/glp111. Epub 2009 Aug 25. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19706698 Free PMC article.
Metabolic effects of intra-abdominal fat in GHRKO mice.
Masternak MM, Bartke A, Wang F, Spong A, Gesing A, Fang Y, Salmon AB, Hughes LF, Liberati T, Boparai R, Kopchick JJ, Westbrook R. Masternak MM, et al. Among authors: wang f. Aging Cell. 2012 Feb;11(1):73-81. doi: 10.1111/j.1474-9726.2011.00763.x. Epub 2011 Nov 28. Aging Cell. 2012. PMID: 22040032 Free PMC article.
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