Jones LA - Search Results

1

Synthesis, [¹⁸F] radiolabeling, and evaluation of poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors for in vivo imaging of PARP-1 using positron emission tomography.

Zhou D, Chu W, Xu J, Jones LA, Peng X, Li S, Chen DL, Mach RH. Zhou D, et al. Among authors: jones la. Bioorg Med Chem. 2014 Mar 1;22(5):1700-7. doi: 10.1016/j.bmc.2014.01.019. Epub 2014 Jan 24. Bioorg Med Chem. 2014. PMID: 24503274 Free PMC article.

2

Carbon-11 labeled sigma2 receptor ligands for imaging breast cancer.

Tu Z, Dence CS, Ponde DE, Jones L, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Nucl Med Biol. 2005 Jul;32(5):423-30. doi: 10.1016/j.nucmedbio.2005.03.008. Nucl Med Biol. 2005. PMID: 15982571

3

[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe.

Xu J, Tu Z, Jones LA, Vangveravong S, Wheeler KT, Mach RH. Xu J, et al. Among authors: jones la. Eur J Pharmacol. 2005 Nov 21;525(1-3):8-17. doi: 10.1016/j.ejphar.2005.09.063. Epub 2005 Nov 10. Eur J Pharmacol. 2005. PMID: 16289030

4

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

5

Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide.

Lee H, Finck BN, Jones LA, Welch MJ, Mach RH. Lee H, et al. Among authors: jones la. Nucl Med Biol. 2006 Oct;33(7):847-54. doi: 10.1016/j.nucmedbio.2006.08.003. Nucl Med Biol. 2006. PMID: 17045164

6

Fluorine-18-labeled benzamide analogues for imaging the sigma2 receptor status of solid tumors with positron emission tomography.

Tu Z, Xu J, Jones LA, Li S, Dumstorff C, Vangveravong S, Chen DL, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Among authors: jones la. J Med Chem. 2007 Jul 12;50(14):3194-204. doi: 10.1021/jm0614883. Epub 2007 Jun 19. J Med Chem. 2007. PMID: 17579383

7

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy.

Kashiwagi H, McDunn JE, Simon PO Jr, Goedegebuure PS, Xu J, Jones L, Chang K, Johnston F, Trinkaus K, Hotchkiss RS, Mach RH, Hawkins WG. Kashiwagi H, et al. Mol Cancer. 2007 Jul 15;6:48. doi: 10.1186/1476-4598-6-48. Mol Cancer. 2007. PMID: 17631687 Free PMC article.

8

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Chu W, Xu J, Zhou D, Zhang F, Jones LA, Wheeler KT, Mach RH. Chu W, et al. Among authors: jones la. Bioorg Med Chem. 2009 Feb 1;17(3):1222-31. doi: 10.1016/j.bmc.2008.12.025. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19119012 Free PMC article.

9

Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter.

Tu Z, Efange SM, Xu J, Li S, Jones LA, Parsons SM, Mach RH. Tu Z, et al. Among authors: jones la. J Med Chem. 2009 Mar 12;52(5):1358-69. doi: 10.1021/jm8012344. J Med Chem. 2009. PMID: 19203271 Free PMC article.

10

[(3)H]4-(Dimethylamino)-N-[4-(4-(2-methoxyphenyl)piperazin- 1-yl)butyl]benzamide, a selective radioligand for dopamine D(3) receptors. I. In vitro characterization.

Xu J, Chu W, Tu Z, Jones LA, Luedtke RR, Perlmutter JS, Mintun MA, Mach RH. Xu J, et al. Among authors: jones la. Synapse. 2009 Sep;63(9):717-28. doi: 10.1002/syn.20652. Synapse. 2009. PMID: 19425052 Free PMC article.

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