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Cell biological steps and checkpoints in accessing NK cell cytotoxicity.
Mace EM, Dongre P, Hsu HT, Sinha P, James AM, Mann SS, Forbes LR, Watkin LB, Orange JS. Mace EM, et al. Immunol Cell Biol. 2014 Mar;92(3):245-55. doi: 10.1038/icb.2013.96. Epub 2014 Jan 21. Immunol Cell Biol. 2014. PMID: 24445602 Free PMC article. Review.
The autoimmune regulator (AIRE), which is defective in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients, is expressed in human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17.
Kumar V, Pedroza LA, Mace EM, Seeholzer S, Cotsarelis G, Condino-Neto A, Payne AS, Orange JS. Kumar V, et al. Among authors: mace em. Am J Pathol. 2011 Mar;178(3):983-8. doi: 10.1016/j.ajpath.2010.12.007. Am J Pathol. 2011. PMID: 21356351 Free PMC article.
Autoimmune regulator (AIRE) contributes to Dectin-1-induced TNF-α production and complexes with caspase recruitment domain-containing protein 9 (CARD9), spleen tyrosine kinase (Syk), and Dectin-1.
Pedroza LA, Kumar V, Sanborn KB, Mace EM, Niinikoski H, Nadeau K, Vasconcelos Dde M, Perez E, Jyonouchi S, Jyonouchi H, Banerjee PP, Ruuskanen O, Condino-Neto A, Orange JS. Pedroza LA, et al. Among authors: mace em. J Allergy Clin Immunol. 2012 Feb;129(2):464-72, 472.e1-3. doi: 10.1016/j.jaci.2011.08.027. Epub 2011 Sep 29. J Allergy Clin Immunol. 2012. PMID: 21962774
Multiple distinct NK-cell synapses.
Mace EM, Orange JS. Mace EM, et al. Blood. 2011 Dec 15;118(25):6475-6. doi: 10.1182/blood-2011-10-381392. Blood. 2011. PMID: 22174302 Free article.
Antibody targeting of anaplastic lymphoma kinase induces cytotoxicity of human neuroblastoma.
Carpenter EL, Haglund EA, Mace EM, Deng D, Martinez D, Wood AC, Chow AK, Weiser DA, Belcastro LT, Winter C, Bresler SC, Vigny M, Mazot P, Asgharzadeh S, Seeger RC, Zhao H, Guo R, Christensen JG, Orange JS, Pawel BR, Lemmon MA, Mossé YP. Carpenter EL, et al. Among authors: mace em. Oncogene. 2012 Nov 15;31(46):4859-67. doi: 10.1038/onc.2011.647. Epub 2012 Jan 23. Oncogene. 2012. PMID: 22266870 Free PMC article.
137 results