Sun Y - Search Results

1

Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.

Li H, Tan M, Jia L, Wei D, Zhao Y, Chen G, Xu J, Zhao L, Thomas D, Beer DG, Sun Y. Li H, et al. Among authors: sun y. J Clin Invest. 2014 Feb;124(2):835-46. doi: 10.1172/JCI70297. Epub 2014 Jan 16. J Clin Invest. 2014. PMID: 24430184 Free PMC article.

2

Histone deacetylase 5 is not a p53 target gene, but its overexpression inhibits tumor cell growth and induces apoptosis.

Huang Y, Tan M, Gosink M, Wang KK, Sun Y. Huang Y, et al. Among authors: sun y. Cancer Res. 2002 May 15;62(10):2913-22. Cancer Res. 2002. PMID: 12019172

3

SAK, a new polo-like kinase, is transcriptionally repressed by p53 and induces apoptosis upon RNAi silencing.

Li J, Tan M, Li L, Pamarthy D, Lawrence TS, Sun Y. Li J, et al. Among authors: sun y. Neoplasia. 2005 Apr;7(4):312-23. doi: 10.1593/neo.04325. Neoplasia. 2005. PMID: 15967108 Free PMC article.

4

A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells.

Bockbrader KM, Tan M, Sun Y. Bockbrader KM, et al. Among authors: sun y. Oncogene. 2005 Nov 10;24(49):7381-8. doi: 10.1038/sj.onc.1208888. Oncogene. 2005. PMID: 16044155

5

CK2 phosphorylation of SAG at Thr10 regulates SAG stability, but not its E3 ligase activity.

He H, Tan M, Pamarthy D, Wang G, Ahmed K, Sun Y. He H, et al. Among authors: sun y. Mol Cell Biochem. 2007 Jan;295(1-2):179-88. doi: 10.1007/s11010-006-9287-3. Epub 2006 Jul 28. Mol Cell Biochem. 2007. PMID: 16874460

6

SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection.

Tan M, Gallegos JR, Gu Q, Huang Y, Li J, Jin Y, Lu H, Sun Y. Tan M, et al. Among authors: sun y. Neoplasia. 2006 Dec;8(12):1042-54. doi: 10.1593/neo.06568. Neoplasia. 2006. PMID: 17217622 Free PMC article.

7

p27 degradation by an ellipticinium series of compound via ubiquitin-proteasome pathway.

Pamarthy D, Tan M, Wu M, Chen J, Yang D, Wang S, Zhang H, Sun Y. Pamarthy D, et al. Among authors: sun y. Cancer Biol Ther. 2007 Mar;6(3):360-6. doi: 10.4161/cbt.6.3.3703. Epub 2007 Mar 12. Cancer Biol Ther. 2007. PMID: 17312389 Free article.

8

SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation.

Gu Q, Tan M, Sun Y. Gu Q, et al. Among authors: sun y. Cancer Res. 2007 Apr 15;67(8):3616-25. doi: 10.1158/0008-5472.CAN-06-4020. Cancer Res. 2007. PMID: 17440073

9

Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2.

Zheng M, Morgan-Lappe SE, Yang J, Bockbrader KM, Pamarthy D, Thomas D, Fesik SW, Sun Y. Zheng M, et al. Among authors: sun y. Cancer Res. 2008 Sep 15;68(18):7570-8. doi: 10.1158/0008-5472.CAN-08-0632. Cancer Res. 2008. PMID: 18794145 Free PMC article.

10

RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27.

Tan M, Davis SW, Saunders TL, Zhu Y, Sun Y. Tan M, et al. Among authors: sun y. Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6203-8. doi: 10.1073/pnas.0812425106. Epub 2009 Mar 26. Proc Natl Acad Sci U S A. 2009. PMID: 19325126 Free PMC article.

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