Jia L - Search Results

1

Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.

Li H, Tan M, Jia L, Wei D, Zhao Y, Chen G, Xu J, Zhao L, Thomas D, Beer DG, Sun Y. Li H, et al. Among authors: jia l. J Clin Invest. 2014 Feb;124(2):835-46. doi: 10.1172/JCI70297. Epub 2014 Jan 16. J Clin Invest. 2014. PMID: 24430184 Free PMC article.

2

ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence.

Jia L, Soengas MS, Sun Y. Jia L, et al. Cancer Res. 2009 Jun 15;69(12):4974-82. doi: 10.1158/0008-5472.CAN-08-4671. Epub 2009 Jun 9. Cancer Res. 2009. PMID: 19509229 Free PMC article.

3

F-box proteins FBXO31 and FBX4 in regulation of cyclin D1 degradation upon DNA damage.

Jia L, Sun Y. Jia L, et al. Pigment Cell Melanoma Res. 2009 Oct;22(5):518-9. doi: 10.1111/j.1755-148X.2009.00611.x. Epub 2009 Jul 23. Pigment Cell Melanoma Res. 2009. PMID: 19645770 Free PMC article. No abstract available.

4

RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival.

Jia L, Sun Y. Jia L, et al. Cell Div. 2009 Aug 6;4:16. doi: 10.1186/1747-1028-4-16. Cell Div. 2009. PMID: 19660140 Free PMC article.

5

Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing target.

Jia L, Yang J, Hao X, Zheng M, He H, Xiong X, Xu L, Sun Y. Jia L, et al. Clin Cancer Res. 2010 Feb 1;16(3):814-24. doi: 10.1158/1078-0432.CCR-09-1592. Epub 2010 Jan 26. Clin Cancer Res. 2010. PMID: 20103673 Free PMC article.

6

RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins.

Jia L, Bickel JS, Wu J, Morgan MA, Li H, Yang J, Yu X, Chan RC, Sun Y. Jia L, et al. J Biol Chem. 2011 Feb 4;286(5):3379-86. doi: 10.1074/jbc.M110.188425. Epub 2010 Nov 29. J Biol Chem. 2011. PMID: 21115485 Free PMC article.

7

SCF E3 ubiquitin ligases as anticancer targets.

Jia L, Sun Y. Jia L, et al. Curr Cancer Drug Targets. 2011 Mar;11(3):347-56. doi: 10.2174/156800911794519734. Curr Cancer Drug Targets. 2011. PMID: 21247385 Free PMC article. Review.

8

Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression.

Jia L, Li H, Sun Y. Jia L, et al. Neoplasia. 2011 Jun;13(6):561-9. doi: 10.1593/neo.11420. Neoplasia. 2011. PMID: 21677879 Free PMC article.

9

SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.

Tan M, Zhao Y, Kim SJ, Liu M, Jia L, Saunders TL, Zhu Y, Sun Y. Tan M, et al. Among authors: jia l. Dev Cell. 2011 Dec 13;21(6):1062-76. doi: 10.1016/j.devcel.2011.09.014. Epub 2011 Nov 23. Dev Cell. 2011. PMID: 22118770 Free PMC article.

10

Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells.

Yang D, Li L, Liu H, Wu L, Luo Z, Li H, Zheng S, Gao H, Chu Y, Sun Y, Liu J, Jia L. Yang D, et al. Among authors: jia l. Cell Death Differ. 2013 Feb;20(2):235-47. doi: 10.1038/cdd.2012.113. Epub 2012 Aug 31. Cell Death Differ. 2013. PMID: 22935614 Free PMC article.

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