Mieszczanek J - Search Results

1

LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.

de la Roche M, Ibrahim AE, Mieszczanek J, Bienz M. de la Roche M, et al. Among authors: mieszczanek j. Cancer Res. 2014 Mar 1;74(5):1495-505. doi: 10.1158/0008-5472.CAN-13-2682. Epub 2014 Jan 13. Cancer Res. 2014. PMID: 24419084 Free PMC article.

2

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.

Mieszczanek J, van Tienen LM, Ibrahim AEK, Winton DJ, Bienz M. Mieszczanek J, et al. Nat Commun. 2019 Feb 13;10(1):724. doi: 10.1038/s41467-018-08164-z. Nat Commun. 2019. PMID: 30760710 Free PMC article.

3

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.

Fiedler M, Sánchez-Barrena MJ, Nekrasov M, Mieszczanek J, Rybin V, Müller J, Evans P, Bienz M. Fiedler M, et al. Among authors: mieszczanek j. Mol Cell. 2008 May 23;30(4):507-18. doi: 10.1016/j.molcel.2008.03.011. Mol Cell. 2008. PMID: 18498752 Free PMC article.

4

A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription.

Mieszczanek J, de la Roche M, Bienz M. Mieszczanek J, et al. Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19324-9. doi: 10.1073/pnas.0806098105. Epub 2008 Nov 26. Proc Natl Acad Sci U S A. 2008. PMID: 19036929 Free PMC article.

5

Stability elements in the LRP6 cytoplasmic tail confer efficient signalling upon DIX-dependent polymerization.

Metcalfe C, Mendoza-Topaz C, Mieszczanek J, Bienz M. Metcalfe C, et al. Among authors: mieszczanek j. J Cell Sci. 2010 May 1;123(Pt 9):1588-99. doi: 10.1242/jcs.067546. Epub 2010 Apr 13. J Cell Sci. 2010. PMID: 20388731 Free PMC article.

6

Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin.

Fiedler M, Mendoza-Topaz C, Rutherford TJ, Mieszczanek J, Bienz M. Fiedler M, et al. Among authors: mieszczanek j. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1937-42. doi: 10.1073/pnas.1017063108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245303 Free PMC article.

7

The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled.

Mendoza-Topaz C, Mieszczanek J, Bienz M. Mendoza-Topaz C, et al. Among authors: mieszczanek j. Open Biol. 2011 Nov;1(3):110013. doi: 10.1098/rsob.110013. Open Biol. 2011. PMID: 22645652 Free PMC article.

8

Evolutionary adaptation of the fly Pygo PHD finger toward recognizing histone H3 tail methylated at arginine 2.

Miller TC, Mieszczanek J, Sánchez-Barrena MJ, Rutherford TJ, Fiedler M, Bienz M. Miller TC, et al. Among authors: mieszczanek j. Structure. 2013 Dec 3;21(12):2208-20. doi: 10.1016/j.str.2013.09.013. Epub 2013 Oct 31. Structure. 2013. PMID: 24183574 Free PMC article.

9

An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.

Fiedler M, Graeb M, Mieszczanek J, Rutherford TJ, Johnson CM, Bienz M. Fiedler M, et al. Among authors: mieszczanek j. Elife. 2015 Aug 27;4:e09073. doi: 10.7554/eLife.09073. Elife. 2015. PMID: 26312500 Free PMC article.

10

Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled.

Mund T, Graeb M, Mieszczanek J, Gammons M, Pelham HR, Bienz M. Mund T, et al. Among authors: mieszczanek j. Open Biol. 2015 Dec;5(12):150185. doi: 10.1098/rsob.150185. Open Biol. 2015. PMID: 26701932 Free PMC article.

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