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Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53.
Kelly GL, Grabow S, Glaser SP, Fitzsimmons L, Aubrey BJ, Okamoto T, Valente LJ, Robati M, Tai L, Fairlie WD, Lee EF, Lindstrom MS, Wiman KG, Huang DC, Bouillet P, Rowe M, Rickinson AB, Herold MJ, Strasser A. Kelly GL, et al. Among authors: fitzsimmons l. Genes Dev. 2014 Jan 1;28(1):58-70. doi: 10.1101/gad.232009.113. Genes Dev. 2014. PMID: 24395247 Free PMC article.
EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins.
Fitzsimmons L, Cartlidge R, Chang C, Sejic N, Galbraith LCA, Suraweera CD, Croom-Carter D, Dewson G, Tierney RJ, Bell AI, Shannon-Lowe C, Herold MJ, Rickinson AB, Colman PM, Huang DCS, Strasser A, Kvansakul M, Rowe M, Kelly GL. Fitzsimmons L, et al. Cell Death Differ. 2020 May;27(5):1554-1568. doi: 10.1038/s41418-019-0435-1. Epub 2019 Oct 23. Cell Death Differ. 2020. PMID: 31645677 Free PMC article.
Epstein-Barr virus and Burkitt lymphoma.
Rowe M, Fitzsimmons L, Bell AI. Rowe M, et al. Among authors: fitzsimmons l. Chin J Cancer. 2014 Dec;33(12):609-19. doi: 10.5732/cjc.014.10190. Epub 2014 Nov 21. Chin J Cancer. 2014. PMID: 25418195 Free PMC article. Review.
VAD chemotherapy as remission induction for multiple myeloma.
Anderson H, Scarffe JH, Ranson M, Young R, Wieringa GS, Morgenstern GR, Fitzsimmons L, Ryder D. Anderson H, et al. Among authors: fitzsimmons l. Br J Cancer. 1995 Feb;71(2):326-30. doi: 10.1038/bjc.1995.65. Br J Cancer. 1995. PMID: 7841049 Free PMC article.
78 results