Yu Y - Search Results

1

Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1.

Wang Y, Lonard DM, Yu Y, Chow DC, Palzkill TG, Wang J, Qi R, Matzuk AJ, Song X, Madoux F, Hodder P, Chase P, Griffin PR, Zhou S, Liao L, Xu J, O'Malley BW. Wang Y, et al. Among authors: yu y. Cancer Res. 2014 Mar 1;74(5):1506-1517. doi: 10.1158/0008-5472.CAN-13-2939. Epub 2014 Jan 3. Cancer Res. 2014. PMID: 24390736 Free PMC article.

2

Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.

Qin L, Chen J, Lu D, Jain P, Yu Y, Cardenas D, Peng X, Yu X, Xu J, Wang J, O'Malley BW, Lonard DM. Qin L, et al. Among authors: yu x, yu y. Endocr Relat Cancer. 2021 Aug 13;28(10):657-670. doi: 10.1530/ERC-20-0402. Endocr Relat Cancer. 2021. PMID: 34310341 Free PMC article.

3

Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.

Wang Y, Lonard DM, Yu Y, Chow DC, Palzkill TG, O'Malley BW. Wang Y, et al. Among authors: yu y. Mol Endocrinol. 2011 Dec;25(12):2041-53. doi: 10.1210/me.2011-1222. Epub 2011 Nov 3. Mol Endocrinol. 2011. PMID: 22053001 Free PMC article.

4

Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor.

Yan F, Yu Y, Chow DC, Palzkill T, Madoux F, Hodder P, Chase P, Griffin PR, O'Malley BW, Lonard DM. Yan F, et al. Among authors: yu y. PLoS One. 2014 Apr 17;9(4):e95243. doi: 10.1371/journal.pone.0095243. eCollection 2014. PLoS One. 2014. PMID: 24743578 Free PMC article.

5

Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death.

Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Wang L, et al. Among authors: yu y. Cancer Cell. 2015 Aug 10;28(2):240-52. doi: 10.1016/j.ccell.2015.07.005. Cancer Cell. 2015. PMID: 26267537 Free PMC article.

6

Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3.

Song X, Chen J, Zhao M, Zhang C, Yu Y, Lonard DM, Chow DC, Palzkill T, Xu J, O'Malley BW, Wang J. Song X, et al. Among authors: yu y. Proc Natl Acad Sci U S A. 2016 May 3;113(18):4970-5. doi: 10.1073/pnas.1604274113. Epub 2016 Apr 15. Proc Natl Acad Sci U S A. 2016. PMID: 27084884 Free PMC article.

7

Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells.

Rohira AD, Yan F, Wang L, Wang J, Zhou S, Lu A, Yu Y, Xu J, Lonard DM, O'Malley BW. Rohira AD, et al. Among authors: yu y. Cancer Res. 2017 Aug 15;77(16):4293-4304. doi: 10.1158/0008-5472.CAN-16-2982. Epub 2017 Jun 13. Cancer Res. 2017. PMID: 28611048 Free PMC article.

8

SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma.

Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, Van Buren G 2nd, McElhany AL, Fisher WE, Lonard DM, O'Malley BW, Wang J. Song X, et al. Among authors: yu y. Cancer Lett. 2019 Feb 1;442:310-319. doi: 10.1016/j.canlet.2018.11.012. Epub 2018 Nov 10. Cancer Lett. 2019. PMID: 30423406 Free PMC article.

9

A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells.

Gilad Y, Eliaz Y, Yu Y, Dean AM, Han SJ, Qin L, O'Malley BW, Lonard DM. Gilad Y, et al. Among authors: yu y. Commun Biol. 2021 Mar 25;4(1):399. doi: 10.1038/s42003-021-01929-1. Commun Biol. 2021. PMID: 33767353 Free PMC article.

10

Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination.

Gilad Y, Eliaz Y, Yu Y, Han SJ, O'Malley BW, Lonard DM. Gilad Y, et al. Among authors: yu y. Sci Rep. 2019 Oct 22;9(1):15099. doi: 10.1038/s41598-019-51537-7. Sci Rep. 2019. PMID: 31641154 Free PMC article.

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