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An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice.
Khan A, Bakhru P, Saikolappan S, Das K, Soudani E, Singh CR, Estrella JL, Zhang D, Pasare C, Ma Y, Sun J, Wang J, Hunter RL, Tony Eissa N, Dhandayuthapani S, Jagannath C. Khan A, et al. Among authors: bakhru p. NPJ Vaccines. 2019 Aug 5;4:34. doi: 10.1038/s41541-019-0122-8. eCollection 2019. NPJ Vaccines. 2019. PMID: 31396406 Free PMC article.
Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity.
Hinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A. Hinz D, et al. Among authors: bakhru p. Clin Exp Allergy. 2016 May;46(5):705-19. doi: 10.1111/cea.12692. Clin Exp Allergy. 2016. PMID: 26662458 Free PMC article.
Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity.
Eskiocak U, Guzman W, Wolf B, Cummings C, Milling L, Wu HJ, Ophir M, Lambden C, Bakhru P, Gilmore DC, Ottinger S, Liu L, McConaughy WK, He SQ, Wang C, Leung CL, Lajoie J, Carson WF 4th, Zizlsperger N, Schmidt MM, Anderson AC, Bobrowicz P, Schuetz TJ, Tighe R. Eskiocak U, et al. Among authors: bakhru p. JCI Insight. 2020 Mar 12;5(5):e133647. doi: 10.1172/jci.insight.133647. JCI Insight. 2020. PMID: 32161196 Free PMC article.
Estrogen turns down "the AIRE".
Bakhru P, Su MA. Bakhru P, et al. J Clin Invest. 2016 Apr 1;126(4):1239-41. doi: 10.1172/JCI86800. Epub 2016 Mar 21. J Clin Invest. 2016. PMID: 26999606 Free PMC article.
12 results