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Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity.
Blanca G, Baldanti F, Paolucci S, Skoblov AY, Victorova L, Hübscher U, Gerna G, Spadari S, Maga G. Blanca G, et al. Among authors: paolucci s. J Biol Chem. 2003 May 2;278(18):15469-72. doi: 10.1074/jbc.C300022200. Epub 2003 Feb 24. J Biol Chem. 2003. PMID: 12601008 Free article.
Gln145Met/Leu changes in human immunodeficiency virus type 1 reverse transcriptase confer resistance to nucleoside and nonnucleoside analogs and impair virus replication.
Paolucci S, Baldanti F, Maga G, Cancio R, Zazzi M, Zavattoni M, Chiesa A, Spadari S, Gerna G. Paolucci S, et al. Antimicrob Agents Chemother. 2004 Dec;48(12):4611-7. doi: 10.1128/AAC.48.12.4611-4617.2004. Antimicrob Agents Chemother. 2004. PMID: 15561833 Free PMC article.
Several amino acid substitutions different from the recently reported Gln145Met change (S. Paolucci, F. Baldanti, M. Tinelli, G. Maga, and G. Gerna, AIDS 17:924-927, 2003) were detected at position 145. ...
Several amino acid substitutions different from the recently reported Gln145Met change (S. Paolucci, F. Baldanti, M. Tinelli, …
411 results