Zheng N - Search Results

1

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.

Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB. Hast BE, et al. Among authors: zheng n. Cancer Res. 2014 Feb 1;74(3):808-17. doi: 10.1158/0008-5472.CAN-13-1655. Epub 2013 Dec 9. Cancer Res. 2014. PMID: 24322982 Free PMC article.

2

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Major MB, et al. Among authors: zheng n. Science. 2007 May 18;316(5827):1043-6. doi: 10.1126/science/1141515. Science. 2007. PMID: 17510365

3

Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein.

Camp ND, James RG, Dawson DW, Yan F, Davison JM, Houck SA, Tang X, Zheng N, Major MB, Moon RT. Camp ND, et al. Among authors: zheng n. J Biol Chem. 2012 Feb 24;287(9):6539-50. doi: 10.1074/jbc.M111.316471. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215675 Free PMC article.

4

Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.

Wang H, Curran EC, Hinds TR, Wang EH, Zheng N. Wang H, et al. Among authors: zheng n. Cell Res. 2014 Dec;24(12):1433-44. doi: 10.1038/cr.2014.148. Epub 2014 Nov 21. Cell Res. 2014. PMID: 25412659 Free PMC article.

5

Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20.

Li H, Lim KS, Kim H, Hinds TR, Jo U, Mao H, Weller CE, Sun J, Chatterjee C, D'Andrea AD, Zheng N. Li H, et al. Among authors: zheng n. Mol Cell. 2016 Jul 21;63(2):249-260. doi: 10.1016/j.molcel.2016.05.031. Epub 2016 Jun 30. Mol Cell. 2016. PMID: 27373336 Free PMC article.

6

Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.

Hsu PL, Li H, Lau HT, Leonen C, Dhall A, Ong SE, Chatterjee C, Zheng N. Hsu PL, et al. Among authors: zheng n. Cell. 2018 Aug 23;174(5):1106-1116.e9. doi: 10.1016/j.cell.2018.06.038. Epub 2018 Aug 9. Cell. 2018. PMID: 30100181 Free PMC article.

7

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation.

Angers S, Thorpe CJ, Biechele TL, Goldenberg SJ, Zheng N, MacCoss MJ, Moon RT. Angers S, et al. Among authors: zheng n. Nat Cell Biol. 2006 Apr;8(4):348-57. doi: 10.1038/ncb1381. Epub 2006 Mar 19. Nat Cell Biol. 2006. PMID: 16547521

8

Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase.

Nangle S, Xing W, Zheng N. Nangle S, et al. Among authors: zheng n. Cell Res. 2013 Dec;23(12):1417-9. doi: 10.1038/cr.2013.136. Epub 2013 Oct 1. Cell Res. 2013. PMID: 24080726 Free PMC article. No abstract available.

9

USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors.

Lim KS, Li H, Roberts EA, Gaudiano EF, Clairmont C, Sambel LA, Ponnienselvan K, Liu JC, Yang C, Kozono D, Parmar K, Yusufzai T, Zheng N, D'Andrea AD. Lim KS, et al. Among authors: zheng n. Mol Cell. 2018 Dec 20;72(6):925-941.e4. doi: 10.1016/j.molcel.2018.10.045. Mol Cell. 2018. PMID: 30576655 Free PMC article.

10

Structural basis of salicylic acid perception by Arabidopsis NPR proteins.

Wang W, Withers J, Li H, Zwack PJ, Rusnac DV, Shi H, Liu L, Yan S, Hinds TR, Guttman M, Dong X, Zheng N. Wang W, et al. Among authors: zheng n. Nature. 2020 Oct;586(7828):311-316. doi: 10.1038/s41586-020-2596-y. Epub 2020 Aug 12. Nature. 2020. PMID: 32788727 Free PMC article.

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