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Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.
Kennedy JJ, Abbatiello SE, Kim K, Yan P, Whiteaker JR, Lin C, Kim JS, Zhang Y, Wang X, Ivey RG, Zhao L, Min H, Lee Y, Yu MH, Yang EG, Lee C, Wang P, Rodriguez H, Kim Y, Carr SA, Paulovich AG. Kennedy JJ, et al. Among authors: yan p. Nat Methods. 2014 Feb;11(2):149-55. doi: 10.1038/nmeth.2763. Epub 2013 Dec 8. Nat Methods. 2014. PMID: 24317253 Free PMC article.
A targeted proteomics-based pipeline for verification of biomarkers in plasma.
Whiteaker JR, Lin C, Kennedy J, Hou L, Trute M, Sokal I, Yan P, Schoenherr RM, Zhao L, Voytovich UJ, Kelly-Spratt KS, Krasnoselsky A, Gafken PR, Hogan JM, Jones LA, Wang P, Amon L, Chodosh LA, Nelson PS, McIntosh MW, Kemp CJ, Paulovich AG. Whiteaker JR, et al. Among authors: yan p. Nat Biotechnol. 2011 Jun 19;29(7):625-34. doi: 10.1038/nbt.1900. Nat Biotechnol. 2011. PMID: 21685906 Free PMC article.
CPTAC Assay Portal: a repository of targeted proteomic assays.
Whiteaker JR, Halusa GN, Hoofnagle AN, Sharma V, MacLean B, Yan P, Wrobel JA, Kennedy J, Mani DR, Zimmerman LJ, Meyer MR, Mesri M, Rodriguez H; Clinical Proteomic Tumor Analysis Consortium (CPTAC); Paulovich AG. Whiteaker JR, et al. Among authors: yan p. Nat Methods. 2014 Jul;11(7):703-4. doi: 10.1038/nmeth.3002. Nat Methods. 2014. PMID: 24972168 Free PMC article. No abstract available.
Proteogenomics connects somatic mutations to signalling in breast cancer.
Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, Gatza ML, Wilkerson M, Perou CM, Yellapantula V, Huang KL, Lin C, McLellan MD, Yan P, Davies SR, Townsend RR, Skates SJ, Wang J, Zhang B, Kinsinger CR, Mesri M, Rodriguez H, Ding L, Paulovich AG, Fenyö D, Ellis MJ, Carr SA; NCI CPTAC. Mertins P, et al. Among authors: yan p. Nature. 2016 Jun 2;534(7605):55-62. doi: 10.1038/nature18003. Epub 2016 May 25. Nature. 2016. PMID: 27251275 Free PMC article.
Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.
Kennedy JJ, Yan P, Zhao L, Ivey RG, Voytovich UJ, Moore HD, Lin C, Pogosova-Agadjanyan EL, Stirewalt DL, Reding KW, Whiteaker JR, Paulovich AG. Kennedy JJ, et al. Among authors: yan p. Mol Cell Proteomics. 2016 Feb;15(2):726-39. doi: 10.1074/mcp.O115.054940. Epub 2015 Nov 30. Mol Cell Proteomics. 2016. PMID: 26621847 Free PMC article.
3,727 results