Ritorto MS - Search Results

1

Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity.

Houde VP, Ritorto MS, Gourlay R, Varghese J, Davies P, Shpiro N, Sakamoto K, Alessi DR. Houde VP, et al. Among authors: ritorto ms. Biochem J. 2014 Feb 15;458(1):41-56. doi: 10.1042/BJ20131324. Biochem J. 2014. PMID: 24295069 Free PMC article.

2

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.

Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM. Kazlauskaite A, et al. Among authors: ritorto ms. Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334. Biochem J. 2014. PMID: 24660806 Free PMC article.

3

The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system.

Strickson S, Campbell DG, Emmerich CH, Knebel A, Plater L, Ritorto MS, Shpiro N, Cohen P. Strickson S, et al. Among authors: ritorto ms. Biochem J. 2013 May 1;451(3):427-37. doi: 10.1042/BJ20121651. Biochem J. 2013. PMID: 23441730 Free PMC article.

4

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry.

Ritorto MS, Ewan R, Perez-Oliva AB, Knebel A, Buhrlage SJ, Wightman M, Kelly SM, Wood NT, Virdee S, Gray NS, Morrice NA, Alessi DR, Trost M. Ritorto MS, et al. Nat Commun. 2014 Aug 27;5:4763. doi: 10.1038/ncomms5763. Nat Commun. 2014. PMID: 25159004 Free PMC article.

5

USP7 small-molecule inhibitors interfere with ubiquitin binding.

Kategaya L, Di Lello P, Rougé L, Pastor R, Clark KR, Drummond J, Kleinheinz T, Lin E, Upton JP, Prakash S, Heideker J, McCleland M, Ritorto MS, Alessi DR, Trost M, Bainbridge TW, Kwok MCM, Ma TP, Stiffler Z, Brasher B, Tang Y, Jaishankar P, Hearn BR, Renslo AR, Arkin MR, Cohen F, Yu K, Peale F, Gnad F, Chang MT, Klijn C, Blackwood E, Martin SE, Forrest WF, Ernst JA, Ndubaku C, Wang X, Beresini MH, Tsui V, Schwerdtfeger C, Blake RA, Murray J, Maurer T, Wertz IE. Kategaya L, et al. Among authors: ritorto ms. Nature. 2017 Oct 26;550(7677):534-538. doi: 10.1038/nature24006. Epub 2017 Oct 18. Nature. 2017. PMID: 29045385

6

High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry-based deubiquitylating enzyme assay for drug discovery.

De Cesare V, Moran J, Traynor R, Knebel A, Ritorto MS, Trost M, McLauchlan H, Hastie CJ, Davies P. De Cesare V, et al. Among authors: ritorto ms. Nat Protoc. 2020 Dec;15(12):4034-4057. doi: 10.1038/s41596-020-00405-0. Epub 2020 Nov 2. Nat Protoc. 2020. PMID: 33139956

7

Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.

Kristariyanto YA, Choi SY, Rehman SA, Ritorto MS, Campbell DG, Morrice NA, Toth R, Kulathu Y. Kristariyanto YA, et al. Among authors: ritorto ms. Biochem J. 2015 Apr 15;467(2):345-52. doi: 10.1042/BJ20141502. Biochem J. 2015. PMID: 25723849 Free PMC article.

8

Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers.

Bett JS, Ritorto MS, Ewan R, Jaffray EG, Virdee S, Chin JW, Knebel A, Kurz T, Trost M, Tatham MH, Hay RT. Bett JS, et al. Among authors: ritorto ms. Biochem J. 2015 Mar 15;466(3):489-98. doi: 10.1042/BJ20141349. Biochem J. 2015. PMID: 25489924 Free PMC article.

9

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation.

McGuire VA, Ruiz-Zorrilla Diez T, Emmerich CH, Strickson S, Ritorto MS, Sutavani RV, Weiβ A, Houslay KF, Knebel A, Meakin PJ, Phair IR, Ashford ML, Trost M, Arthur JS. McGuire VA, et al. Among authors: ritorto ms. Sci Rep. 2016 Aug 8;6:31159. doi: 10.1038/srep31159. Sci Rep. 2016. PMID: 27498693 Free PMC article.

10

Hydrophilic strong anion exchange (hSAX) chromatography for highly orthogonal peptide separation of complex proteomes.

Ritorto MS, Cook K, Tyagi K, Pedrioli PG, Trost M. Ritorto MS, et al. J Proteome Res. 2013 Jun 7;12(6):2449-57. doi: 10.1021/pr301011r. Epub 2013 Jan 7. J Proteome Res. 2013. PMID: 23294059 Free PMC article.

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