Manning BD - Search Results

1

The TSC-mTOR pathway regulates macrophage polarization.

Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. Byles V, et al. Among authors: manning bd. Nat Commun. 2013;4:2834. doi: 10.1038/ncomms3834. Nat Commun. 2013. PMID: 24280772 Free PMC article.

2

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.

Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J. Tee AR, et al. Among authors: manning bd. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13571-6. doi: 10.1073/pnas.202476899. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271141 Free PMC article.

3

United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling.

Manning BD, Cantley LC. Manning BD, et al. Biochem Soc Trans. 2003 Jun;31(Pt 3):573-8. doi: 10.1042/bst0310573. Biochem Soc Trans. 2003. PMID: 12773158 Review.

4

The LKB1 tumor suppressor negatively regulates mTOR signaling.

Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, Cantley LC. Shaw RJ, et al. Among authors: manning bd. Cancer Cell. 2004 Jul;6(1):91-9. doi: 10.1016/j.ccr.2004.06.007. Cancer Cell. 2004. PMID: 15261145 Free article.

5

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2.

Manning BD, Logsdon MN, Lipovsky AI, Abbott D, Kwiatkowski DJ, Cantley LC. Manning BD, et al. Genes Dev. 2005 Aug 1;19(15):1773-8. doi: 10.1101/gad.1314605. Epub 2005 Jul 18. Genes Dev. 2005. PMID: 16027169 Free PMC article.

6

S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.

Zhang HH, Lipovsky AI, Dibble CC, Sahin M, Manning BD. Zhang HH, et al. Among authors: manning bd. Mol Cell. 2006 Oct 20;24(2):185-97. doi: 10.1016/j.molcel.2006.09.019. Mol Cell. 2006. PMID: 17052453 Free PMC article.

7

Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis.

Ozcan U, Ozcan L, Yilmaz E, Düvel K, Sahin M, Manning BD, Hotamisligil GS. Ozcan U, et al. Among authors: manning bd. Mol Cell. 2008 Mar 14;29(5):541-51. doi: 10.1016/j.molcel.2007.12.023. Mol Cell. 2008. PMID: 18342602 Free PMC article.

8

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2.

Huang J, Dibble CC, Matsuzaki M, Manning BD. Huang J, et al. Among authors: manning bd. Mol Cell Biol. 2008 Jun;28(12):4104-15. doi: 10.1128/MCB.00289-08. Epub 2008 Apr 14. Mol Cell Biol. 2008. PMID: 18411301 Free PMC article.

9

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth.

Huang J, Manning BD. Huang J, et al. Among authors: manning bd. Biochem J. 2008 Jun 1;412(2):179-90. doi: 10.1042/BJ20080281. Biochem J. 2008. PMID: 18466115 Free PMC article. Review.

10

The mammalian target of rapamycin complex 1 regulates leptin biosynthesis in adipocytes at the level of translation: the role of the 5'-untranslated region in the expression of leptin messenger ribonucleic acid.

Chakrabarti P, Anno T, Manning BD, Luo Z, Kandror KV. Chakrabarti P, et al. Among authors: manning bd. Mol Endocrinol. 2008 Oct;22(10):2260-7. doi: 10.1210/me.2008-0148. Epub 2008 Jul 24. Mol Endocrinol. 2008. PMID: 18653778 Free PMC article.

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