Wilson IA - Search Results

1

The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P. Sok D, et al. Among authors: wilson ia. PLoS Pathog. 2013;9(11):e1003754. doi: 10.1371/journal.ppat.1003754. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278016 Free PMC article. Clinical Trial.

2

Crystal structure of the principal neutralization site of HIV-1.

Ghiara JB, Stura EA, Stanfield RL, Profy AT, Wilson IA. Ghiara JB, et al. Among authors: wilson ia. Science. 1994 Apr 1;264(5155):82-5. doi: 10.1126/science.7511253. Science. 1994. PMID: 7511253

3

Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.

Ghiara JB, Ferguson DC, Satterthwait AC, Dyson HJ, Wilson IA. Ghiara JB, et al. Among authors: wilson ia. J Mol Biol. 1997 Feb 14;266(1):31-9. doi: 10.1006/jmbi.1996.0768. J Mol Biol. 1997. PMID: 9054968

4

Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1.

Saphire EO, Parren PW, Barbas CF 3rd, Burton DR, Wilson IA. Saphire EO, et al. Among authors: wilson ia. Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):168-71. doi: 10.1107/s0907444900017376. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11134947

5

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, Wilson IA. Saphire EO, et al. Among authors: wilson ia. Science. 2001 Aug 10;293(5532):1155-9. doi: 10.1126/science.1061692. Science. 2001. PMID: 11498595

6

Contrasting IgG structures reveal extreme asymmetry and flexibility.

Saphire EO, Stanfield RL, Crispin MD, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Saphire EO, et al. Among authors: wilson ia. J Mol Biol. 2002 May 24;319(1):9-18. doi: 10.1016/S0022-2836(02)00244-9. J Mol Biol. 2002. PMID: 12051932

7

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, Burton DR. Scanlan CN, et al. Among authors: wilson ia. J Virol. 2002 Jul;76(14):7306-21. doi: 10.1128/jvi.76.14.7306-7321.2002. J Virol. 2002. PMID: 12072529 Free PMC article.

8

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

Pantophlet R, Ollmann Saphire E, Poignard P, Parren PW, Wilson IA, Burton DR. Pantophlet R, et al. Among authors: wilson ia. J Virol. 2003 Jan;77(1):642-58. doi: 10.1128/jvi.77.1.642-658.2003. J Virol. 2003. PMID: 12477867 Free PMC article.

9

Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.

Zwick MB, Parren PW, Saphire EO, Church S, Wang M, Scott JK, Dawson PE, Wilson IA, Burton DR. Zwick MB, et al. Among authors: wilson ia. J Virol. 2003 May;77(10):5863-76. doi: 10.1128/jvi.77.10.5863-5876.2003. J Virol. 2003. PMID: 12719580 Free PMC article.

10

Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design.

Pantophlet R, Wilson IA, Burton DR. Pantophlet R, et al. Among authors: wilson ia. J Virol. 2003 May;77(10):5889-901. doi: 10.1128/jvi.77.10.5889-5901.2003. J Virol. 2003. PMID: 12719582 Free PMC article.

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