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A phase 2 study of ruxolitinib, an oral JAK1 and JAK2 Inhibitor, in patients with advanced polycythemia vera who are refractory or intolerant to hydroxyurea.
Verstovsek S, Passamonti F, Rambaldi A, Barosi G, Rosen PJ, Rumi E, Gattoni E, Pieri L, Guglielmelli P, Elena C, He S, Contel N, Mookerjee B, Sandor V, Cazzola M, Kantarjian HM, Barbui T, Vannucchi AM. Verstovsek S, et al. Among authors: rumi e. Cancer. 2014 Feb 15;120(4):513-20. doi: 10.1002/cncr.28441. Cancer. 2014. PMID: 24258498 Free PMC article. Clinical Trial.
Relation between JAK2 (V617F) mutation status, granulocyte activation, and constitutive mobilization of CD34+ cells into peripheral blood in myeloproliferative disorders.
Passamonti F, Rumi E, Pietra D, Della Porta MG, Boveri E, Pascutto C, Vanelli L, Arcaini L, Burcheri S, Malcovati L, Lazzarino M, Cazzola M. Passamonti F, et al. Among authors: rumi e. Blood. 2006 May 1;107(9):3676-82. doi: 10.1182/blood-2005-09-3826. Epub 2005 Dec 22. Blood. 2006. PMID: 16373657 Free article.
JAK2 (V617F) mutation in healthy individuals.
Passamonti F, Rumi E, Pietra D, Lazzarino M, Cazzola M. Passamonti F, et al. Among authors: rumi e. Br J Haematol. 2007 Feb;136(4):678-9. doi: 10.1111/j.1365-2141.2006.06483.x. Br J Haematol. 2007. PMID: 17223913 Free article. No abstract available.
202 results