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Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
Nagy N, Czepiel KS, Kaber G, Stefanovski D, Hargil A, Pennetzdorfer N, Targ R, Reghupaty SC, Wight TN, Vernon RB, Hull-Meichle RL, Marshall P, Medina CO, Martinez H, Kalinowski A, Paladini RD, Garantziotis S, Knowles JW, Bollyky PL. Nagy N, et al. Cells. 2024 Oct 18;13(20):1727. doi: 10.3390/cells13201727. Cells. 2024. PMID: 39451245 Free PMC article.
Clinical trials for Lennox-Gastaut syndrome: Challenges and priorities.
Knowles JK, Warren AEL, Mohamed IS, Stafstrom CE, Koh HY, Samanta D, Shellhaas RA, Gupta G, Dixon-Salazar T, Tran L, Bhatia S, McCabe JM, Patel AD, Grinspan ZM. Knowles JK, et al. Ann Clin Transl Neurol. 2024 Oct 23. doi: 10.1002/acn3.52211. Online ahead of print. Ann Clin Transl Neurol. 2024. PMID: 39440617 Free article. Review.
Genome-wide association study meta-analysis of 9,619 cases with tic disorders.
Strom NI, Halvorsen MW, Grove J, Ásbjörnsdóttir B, Luðvígsson P, Thorarensen Ó, de Schipper E, Boberg J, Andrén P, Tian C; PGC TS-working group; 23andMe Research Team; Als TD, Nissen JB, Meier SM, Bybjerg-Grauholm J, Hougaard DM, Werge T, Børglum AD, Hinds DA, Rück C, Mataix-Cols D, Stefánsson H, Stefansson K, Crowley JJ, Mattheisen M. Strom NI, et al. Biol Psychiatry. 2024 Oct 8:S0006-3223(24)01648-2. doi: 10.1016/j.biopsych.2024.07.025. Online ahead of print. Biol Psychiatry. 2024. PMID: 39389409 Free article.
One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.
Kim DS, Chu EL, Keamy-Minor EE, Paranjpe ID, Tang WL, O'Sullivan JW, Desai YB, Liu MB, Munsey E, Hecker K, Cuenco I, Kao B, Bacolor E, Bonnett C, Linder A, Lacar K, Robles N, Lamendola C, Smith A, Knowles JW, Perez MV, Kawana M, Sallam KI, Weldy CS, Wheeler MT, Parikh VN, Salisbury H, Ashley EA; Stanford Center for Inherited Cardiovascular Disease. Kim DS, et al. Front Cardiovasc Med. 2024 Aug 30;11:1429230. doi: 10.3389/fcvm.2024.1429230. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 39314763 Free PMC article.
A functional genomic framework to elucidate novel causal metabolic dysfunction-associated fatty liver disease genes.
Saliba-Gustafsson P, Justesen JM, Ranta A, Sharma D, Bielczyk-Maczynska E, Li J, Najmi LA, Apodaka M, Aspichueta P, Björck HM, Eriksson P, Schurr TM, Franco-Cereceda A, Gloudemans M, Mujica E, den Hoed M, Assimes TL, Quertermous T, Carcamo-Orive I, Park CY, Knowles JW. Saliba-Gustafsson P, et al. Hepatology. 2024 Aug 27. doi: 10.1097/HEP.0000000000001066. Online ahead of print. Hepatology. 2024. PMID: 39190705
Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes.
Yu GZ, Krentz NAJ, Bentley L, Zhao M, Paphiti K, Sun H, Honecker J, Nygård M, Dashti H, Bai Y, Reid M, Thaman S, Wabitsch M, Rajesh V, Yang J, Mattis KK, Abaitua F, Casero R, Hauner H, Knowles JW, Wu JY, Mandrup S, Claussnitzer M, Svensson KJ, Cox RD, Gloyn AL. Yu GZ, et al. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605923. doi: 10.1101/2024.07.30.605923. bioRxiv. 2024. PMID: 39131393 Free PMC article. Preprint.
1,587 results