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Page 1
Mechanistic investigations of test article-induced pancreatic toxicity at the endocrine-exocrine interface in the rat.
Brenneman KA, Ramaiah SK, Rohde CM, Messing DM, O'Neil SP, Gauthier LM, Stewart ZS, Mantena SR, Shevlin KM, Leonard CG, Sokolowski SA, Lin H, Carraher DC, Jesson MI, Tomlinson L, Zhan Y, Bobrowski WF, Bailey SA, Vogel WM, Morris DL, Whiteley LO, Davis JW 2nd. Brenneman KA, et al. Among authors: sokolowski sa. Toxicol Pathol. 2014 Jan;42(1):229-42. doi: 10.1177/0192623313508851. Epub 2013 Nov 13. Toxicol Pathol. 2014. PMID: 24226507
Pregabalin induces hepatic hypoxia and increases endothelial cell proliferation in mice, a process inhibited by dietary vitamin E supplementation.
Criswell KA, Cook JC, Morse D, Lawton M, Somps C, Obert L, Roy M, Sokolowski S, Koza-Taylor P, Colangelo J, Navetta K, Brady J, Pegg D, Wojcinski Z, Rahbari R, Duddy S, Anderson T. Criswell KA, et al. Toxicol Sci. 2012 Jul;128(1):42-56. doi: 10.1093/toxsci/kfs148. Epub 2012 Apr 26. Toxicol Sci. 2012. PMID: 22539613
Liver Microvascular Injury and Thrombocytopenia of Antibody-Calicheamicin Conjugates in Cynomolgus Monkeys-Mechanism and Monitoring.
Guffroy M, Falahatpisheh H, Biddle K, Kreeger J, Obert L, Walters K, Goldstein R, Boucher G, Coskran T, Reagan W, Sullivan D, Huang C, Sokolowski S, Giovanelli R, Gerber HP, Finkelstein M, Khan N. Guffroy M, et al. Clin Cancer Res. 2017 Apr 1;23(7):1760-1770. doi: 10.1158/1078-0432.CCR-16-0939. Epub 2016 Sep 28. Clin Cancer Res. 2017. PMID: 27683177
Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity.
Fisher TS, Kamperschroer C, Oliphant T, Love VA, Lira PD, Doyonnas R, Bergqvist S, Baxi SM, Rohner A, Shen AC, Huang C, Sokolowski SA, Sharp LL. Fisher TS, et al. Among authors: sokolowski sa. Cancer Immunol Immunother. 2012 Oct;61(10):1721-33. doi: 10.1007/s00262-012-1237-1. Epub 2012 Mar 11. Cancer Immunol Immunother. 2012. PMID: 22406983 Free PMC article.
Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014.
Lanz TA, Wood KM, Richter KE, Nolan CE, Becker SL, Pozdnyakov N, Martin BA, Du P, Oborski CE, Wood DE, Brown TM, Finley JE, Sokolowski SA, Hicks CD, Coffman KJ, Geoghegan KF, Brodney MA, Liston D, Tate B. Lanz TA, et al. Among authors: sokolowski sa. J Pharmacol Exp Ther. 2010 Jul;334(1):269-77. doi: 10.1124/jpet.110.167379. Epub 2010 Apr 2. J Pharmacol Exp Ther. 2010. PMID: 20363853
Diamide amino-imidazoles: a novel series of γ-secretase inhibitors for the treatment of Alzheimer's disease.
Brodney MA, Auperin DD, Becker SL, Bronk BS, Brown TM, Coffman KJ, Finley JE, Hicks CD, Karmilowicz MJ, Lanz TA, Liston D, Liu X, Martin BA, Nelson RB, Nolan CE, Oborski CE, Parker CP, Richter KE, Pozdnyakov N, Sahagan BG, Schachter JB, Sokolowski SA, Tate B, Van Deusen JW, Wood DE, Wood KM. Brodney MA, et al. Among authors: sokolowski sa. Bioorg Med Chem Lett. 2011 May 1;21(9):2631-6. doi: 10.1016/j.bmcl.2010.12.117. Epub 2010 Dec 30. Bioorg Med Chem Lett. 2011. PMID: 21269825
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